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    CG4278 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 34970, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG4278provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0014092
    Locus tag
    Dmel_CG4278
    See related
    AllianceGenome:FB:FBgn0014092
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    anon-35F/36A; BG:DS02740.16; Dmel\CG4278; un5
    Summary
    Predicted to be active in mitochondrion. Is expressed in adult heart and organism. Orthologous to human NIF3L1 (NGG1 interacting factor 3 like 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG4278 in Genome Data Viewer
    Location:
    35F1-35F1; 2-52 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (16327069..16328131)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (16327069..16328131)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene cornichon Neighboring gene fizzy Neighboring gene cactus Neighboring gene mitochondrial ribosomal protein L4 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. cactus, a gene involved in dorsoventral pattern formation of Drosophila, is related to the I kappa B gene family of vertebrates. Geisler R, et al. Cell, 1992 Nov 13. PMID 1423618
    2. Ubiquilins regulate autophagic flux through mTOR signalling and lysosomal acidification. Şentürk M, et al. Nat Cell Biol, 2019 Mar. PMID 30804504, Free PMC Article
    3. An exploration of the sequence of a 2.9-Mb region of the genome of Drosophila melanogaster: the Adh region. Ashburner M, et al. Genetics, 1999 Sep. PMID 10471707, Free PMC Article
    4. Identification of novel genes associated with longevity in Drosophila melanogaster - a computational approach. Hall BS, et al. Aging (Albany NY), 2019 Dec 3. PMID 31794428, Free PMC Article
    5. Human R1441C LRRK2 regulates the synaptic vesicle proteome and phosphoproteome in a Drosophila model of Parkinson's disease. Islam MS, et al. Hum Mol Genet, 2016 Dec 15. PMID 27794539, Free PMC Article

    See all (31) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG4278-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      16327069..16328131
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_135946.3 → NP_609790.1  uncharacterized protein Dmel_CG4278 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_609790.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9NK57, Q9VJL4
      Related
      FBpp0080392
      Conserved Domains (1) summary
      pfam01784
      Location:16 → 251
      NIF3; NIF3 (NGG1p interacting factor 3)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9NK57.3 Q9NK57

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Chemical Information
    Molecular Biology Databases
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