Mrps5 mitochondrial ribosomal protein S5 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Mrps5provided by MGI
Official Full Name: mitochondrial ribosomal protein S5provided by MGI
Primary source: MGI:MGI:1924971
See related: Ensembl:ENSMUSG00000027374 AllianceGenome:MGI:1924971
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: 1620401I16Rik
Summary: Predicted to be a structural constituent of ribosome. Predicted to be involved in translation. Located in mitochondrion. Is expressed in several structures, including early conceptus; gonad; heart; liver; and metanephros. Orthologous to human MRPS5 (mitochondrial ribosomal protein S5). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Ubiquitous expression in CNS E11.5 (RPKM 26.9), CNS E18 (RPKM 25.3) and 28 other tissues See more
Orthologs: human all
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Genomic context

Location:: 2 F1; 2 62.05 cM

Exon count:: 12

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	2	NC_000068.8 (127429346..127445906)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	2	NC_000068.7 (127587426..127603986)

Chromosome 2 - NC_000068.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Phenotype of Mrps5-Associated Phylogenetic Polymorphisms Is Intimately Linked to Mitoribosomal Misreading.
Title: Phenotype of Mrps5-Associated Phylogenetic Polymorphisms Is Intimately Linked to Mitoribosomal Misreading.

Submit: New GeneRIF Correction

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Endonuclease-mediated (2)
Targeted (4) 1 citation

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

AI850294 (e-PCR)
- UniSTS:178700

NoName (e-PCR)
- UniSTS:234519

BB165757 (e-PCR)
- UniSTS:207394

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables RNA binding	IEA Inferred from Electronic Annotation more info
enables structural constituent of ribosome	IBA Inferred from Biological aspect of Ancestor more info
enables structural constituent of ribosome	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in mitochondrial translation	NAS Non-traceable Author Statement more info	PubMed
involved_in translation	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
located_in mitochondrial inner membrane	NAS Non-traceable Author Statement more info	PubMed
part_of mitochondrial small ribosomal subunit	IBA Inferred from Biological aspect of Ancestor more info
part_of mitochondrial small ribosomal subunit	ISO Inferred from Sequence Orthology more info
part_of mitochondrial small ribosomal subunit	ISS Inferred from Sequence or Structural Similarity more info
part_of mitochondrial small ribosomal subunit	NAS Non-traceable Author Statement more info	PubMed
located_in mitochondrion	HDA more info	PubMed
located_in mitochondrion	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: small ribosomal subunit protein uS5m

Names: 28S ribosomal protein S5, mitochondrial; MRP-S5; S5mt

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_029963.2 → NP_084239.1 small ribosomal subunit protein uS5m

See identical proteins and their annotated locations for NP_084239.1

Status: PROVISIONAL

Source sequence(s)

AB049941

Consensus CDS

CCDS16706.1

UniProtKB/Swiss-Prot

Q99N87

UniProtKB/TrEMBL

Q3U2U4

Related

ENSMUSP00000028852.7, ENSMUST00000028852.13

Conserved Domains (3) summary

TIGR01021
Location:219 → 374

rpsE_bact; ribosomal protein S5, bacterial/organelle type

pfam00333
Location:220 → 285

Ribosomal_S5; Ribosomal protein S5, N-terminal domain

pfam03719
Location:299 → 367

Ribosomal_S5_C; Ribosomal protein S5, C-terminal domain