U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    Zfp870 zinc finger protein 870 [ Mus musculus (house mouse) ]

    Gene ID: 240066, updated on 9-Dec-2024

    Summary

    Official Symbol
    Zfp870provided by MGI
    Official Full Name
    zinc finger protein 870provided by MGI
    Primary source
    MGI:MGI:3029586
    See related
    Ensembl:ENSMUSG00000095325 AllianceGenome:MGI:3029586
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Summary
    Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in nervous system and neural retina. [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in CNS E11.5 (RPKM 1.6), CNS E18 (RPKM 1.4) and 26 other tissues See more
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Zfp870 in Genome Data Viewer
    Location:
    17 B1; 17 17.98 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (33098193..33110621, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (32879221..32891641, complement)

    Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene predicted gene 7059 Neighboring gene predicted gene, 50050 Neighboring gene STARR-seq mESC enhancer starr_42396 Neighboring gene zinc finger protein 870 pseudogene Neighboring gene STARR-seq mESC enhancer starr_42397 Neighboring gene CapStarr-seq enhancer MGSCv37_chr17:33028261-33028519 Neighboring gene STARR-seq mESC enhancer starr_42399 Neighboring gene STARR-seq mESC enhancer starr_42400 Neighboring gene cytochrome P450, family 4, subfamily f, polypeptide 14 Neighboring gene cytochrome P450, family 4, subfamily f, polypeptide 13 Neighboring gene CapStarr-seq enhancer MGSCv37_chr17:33084248-33084483

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    General gene information

    Markers

    Clone Names

    • MGC86136

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001425928.1NP_001412857.1  zinc finger protein 870 isoform 1

      Status: VALIDATED

      Source sequence(s)
      CT033772
    2. NM_207245.3NP_997128.1  zinc finger protein 870 isoform 2

      See identical proteins and their annotated locations for NP_997128.1

      Status: VALIDATED

      Source sequence(s)
      CT033772
      Consensus CDS
      CCDS89069.1
      UniProtKB/TrEMBL
      Q6NZJ3
      Related
      ENSMUSP00000154207.2, ENSMUST00000228075.3
      Conserved Domains (6) summary
      smart00349
      Location:453
      KRAB; krueppel associated box
      COG5048
      Location:360548
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:364384
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:443
      KRAB; KRAB box
      pfam13465
      Location:376399
      zf-H2C2_2; Zinc-finger double domain
      cl19284
      Location:265321
      Ribosomal_L37ae; Ribosomal L37ae protein family

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000083.7 Reference GRCm39 C57BL/6J

      Range
      33098193..33110621 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036160603.1XP_036016496.1  zinc finger protein 870 isoform X2

      Conserved Domains (2) summary
      COG5048
      Location:206394
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:210230
      ZF_C2H2; C2H2 Zn finger [structural motif]