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    ppp2r5e.L protein phosphatase 2 regulatory subunit B', epsilon L homeolog [ Xenopus laevis (African clawed frog) ]

    Gene ID: 399166, updated on 4-Jan-2025

    Summary

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    Official Symbol
    ppp2r5e.L
    Official Full Name
    protein phosphatase 2 regulatory subunit B', epsilon L homeolog
    Primary source
    Xenbase:XB-GENE-17337207
    Locus tag
    XELAEV_18039784mg
    See related
    EnsemblRapid:ENSXLAG00005030178 AllianceGenome:Xenbase:XB-GENE-17337207
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Xenopus laevis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
    Also known as
    ppp2r5e1
    Summary
    Predicted to enable protein phosphatase regulator activity. Predicted to act upstream of or within signal transduction. Predicted to be part of protein phosphatase type 2A complex. Orthologous to human PPP2R5E (protein phosphatase 2 regulatory subunit B'epsilon). [provided by Alliance of Genome Resources, Jan 2025]
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    Genomic context

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    See ppp2r5e.L in Genome Data Viewer
    Location:
    chromosome: 8L
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 8L NC_054385.1 (92675876..92729403)
    100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 8L NC_030738.1 (77949122..78002954)

    Chromosome 8L - NC_054385.1Genomic Context describing neighboring genes Neighboring gene WD repeat domain 89 L homeolog Neighboring gene uncharacterized LOC121397093 Neighboring gene glycoprotein hormone beta 5 L homeolog Neighboring gene ras homolog family member J L homeolog

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A positive role for the PP2A catalytic subunit in Wnt signal transduction. Ratcliffe MJ, et al. J Biol Chem, 2000 Nov 17. PMID 11007767

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by Xenbase

    Function Evidence Code Pubs
    enables protein phosphatase regulator activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of protein phosphatase type 2A complex IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    protein phosphatase 2 regulatory subunit B', epsilon L homeolog; protein phosphatase-2A B'epsilon subunit

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001090401.1 → NP_001083870.1  protein phosphatase 2 regulatory subunit B', epsilon L homeolog

      See identical proteins and their annotated locations for NP_001083870.1

      Status: PROVISIONAL

      Source sequence(s)
      AF298157
      UniProtKB/TrEMBL
      A0A974C8C1, Q9DF48
      Related
      ENSXLAP00005090248.1, ENSXLAT00005091925.1
      Conserved Domains (2) summary
      pfam01603
      Location:55 → 435
      B56; Protein phosphatase 2A regulatory B subunit (B56 family)
      cl27532
      Location:2 → 67
      B56; Protein phosphatase 2A regulatory B subunit (B56 family)

    RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Xenopus_laevis_v10.1 Primary Assembly

    Genomic

    1. NC_054385.1 Reference Xenopus_laevis_v10.1 Primary Assembly

      Range
      92675876..92729403
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_041571953.1 → XP_041427887.1  protein phosphatase-2A B'epsilon subunit isoform X2

      UniProtKB/TrEMBL
      A0A8J1LED0, A0A974C8C1
      Conserved Domains (2) summary
      PLN00122
      Location:364 → 434
      PLN00122; serine/threonine protein phosphatase 2A; Provisional
      cl27532
      Location:7 → 72
      B56; Protein phosphatase 2A regulatory B subunit (B56 family)

    2. XM_041571952.1 → XP_041427886.1  protein phosphatase-2A B'epsilon subunit isoform X1

      UniProtKB/TrEMBL
      A0A8J1LEP1, A0A974C8C1
      Related
      ENSXLAP00005090660.1, ENSXLAT00005092339.1
      Conserved Domains (2) summary
      pfam01603
      Location:60 → 440
      B56; Protein phosphatase 2A regulatory B subunit (B56 family)
      cl27532
      Location:7 → 72
      B56; Protein phosphatase 2A regulatory B subunit (B56 family)

    3. XM_041571954.1 → XP_041427888.1  protein phosphatase-2A B'epsilon subunit isoform X3

      UniProtKB/TrEMBL
      A0A974C8C1, Q9DF48
      Conserved Domains (2) summary
      pfam01603
      Location:55 → 435
      B56; Protein phosphatase 2A regulatory B subunit (B56 family)
      cl27532
      Location:2 → 67
      B56; Protein phosphatase 2A regulatory B subunit (B56 family)

    4. XM_041571956.1 → XP_041427890.1  protein phosphatase-2A B'epsilon subunit isoform X3

      UniProtKB/TrEMBL
      A0A974C8C1, Q9DF48
      Conserved Domains (2) summary
      pfam01603
      Location:55 → 435
      B56; Protein phosphatase 2A regulatory B subunit (B56 family)
      cl27532
      Location:2 → 67
      B56; Protein phosphatase 2A regulatory B subunit (B56 family)

    5. XM_041571955.1 → XP_041427889.1  protein phosphatase-2A B'epsilon subunit isoform X3

      UniProtKB/TrEMBL
      A0A974C8C1, Q9DF48
      Related
      ENSXLAP00005090444.1, ENSXLAT00005092121.1
      Conserved Domains (2) summary
      pfam01603
      Location:55 → 435
      B56; Protein phosphatase 2A regulatory B subunit (B56 family)
      cl27532
      Location:2 → 67
      B56; Protein phosphatase 2A regulatory B subunit (B56 family)

    6. XM_041571957.1 → XP_041427891.1  protein phosphatase-2A B'epsilon subunit isoform X3

      UniProtKB/TrEMBL
      A0A974C8C1, Q9DF48
      Conserved Domains (2) summary
      pfam01603
      Location:55 → 435
      B56; Protein phosphatase 2A regulatory B subunit (B56 family)
      cl27532
      Location:2 → 67
      B56; Protein phosphatase 2A regulatory B subunit (B56 family)
    Nucleotide Protein Strain
    Heading Accession and Version

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