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    Rpusd1 RNA pseudouridine synthase domain containing 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 287148, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Rpusd1provided by RGD
    Official Full Name
    RNA pseudouridine synthase domain containing 1provided by RGD
    Primary source
    RGD:1304934
    See related
    EnsemblRapid:ENSRNOG00000023639 AllianceGenome:RGD:1304934
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1304934
    Summary
    Predicted to enable pseudouridine synthase activity. Predicted to be involved in enzyme-directed rRNA pseudouridine synthesis. Orthologous to human RPUSD1 (RNA pseudouridine synthase domain containing 1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Brain (RPKM 49.9), Thymus (RPKM 34.5) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Rpusd1 in Genome Data Viewer
    Location:
    10q12
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (15255806..15259730)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (14751310..14755213)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (15099104..15102968)

    Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC120095315 Neighboring gene G protein subunit gamma 13 Neighboring gene chromosome transmission fidelity factor 18 Neighboring gene mesothelin-like Neighboring gene mesothelin

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    RNA pseudouridylate synthase domain-containing protein 1
    Names
    RNA pseudouridylate synthase domain containing 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001105774.1 → NP_001099244.1  RNA pseudouridylate synthase domain-containing protein 1

      See identical proteins and their annotated locations for NP_001099244.1

      Status: PROVISIONAL

      Source sequence(s)
      CH473948
      UniProtKB/TrEMBL
      A6HD41, B1WC14, F7F6F2
      Conserved Domains (1) summary
      cd02869
      Location:18 → 215
      PseudoU_synth_RluA_like; Pseudouridine synthase, RluA family

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086028.1 Reference GRCr8

      Range
      15255806..15259730
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006245937.5 → XP_006245999.1  RNA pseudouridylate synthase domain-containing protein 1 isoform X1

      See identical proteins and their annotated locations for XP_006245999.1

      UniProtKB/TrEMBL
      A6HD41, B1WC14, F7F6F2
      Related
      ENSRNOP00000015206.5, ENSRNOT00000015206.8
      Conserved Domains (1) summary
      cd02869
      Location:18 → 215
      PseudoU_synth_RluA_like; Pseudouridine synthase, RluA family

    2. XM_063268569.1 → XP_063124639.1  RNA pseudouridylate synthase domain-containing protein 1 isoform X2

    3. XM_039085363.2 → XP_038941291.1  RNA pseudouridylate synthase domain-containing protein 1 isoform X2

      Conserved Domains (1) summary
      cd02869
      Location:18 → 170
      PseudoU_synth_RluA_like; Pseudouridine synthase, RluA family
    Nucleotide Protein Strain
    Heading Accession and Version

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