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    Lmf2 lipase maturation factor 2 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 315218, updated on 9-Dec-2024

    Summary

    Official Symbol
    Lmf2provided by RGD
    Official Full Name
    lipase maturation factor 2provided by RGD
    Primary source
    RGD:1306274
    See related
    EnsemblRapid:ENSRNOG00000030633 AllianceGenome:RGD:1306274
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Tmem112b; RGD1306274
    Summary
    Predicted to be involved in protein maturation. Predicted to be active in endoplasmic reticulum membrane. Orthologous to human LMF2 (lipase maturation factor 2). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Lung (RPKM 124.5), Kidney (RPKM 73.9) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Lmf2 in Genome Data Viewer
    Location:
    7q34
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 7 NC_086025.1 (122297971..122302423, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 7 NC_051342.1 (120418343..120422825, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 7 NC_005106.4 (130322018..130326470, complement)

    Chromosome 7 - NC_086025.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC102549998 Neighboring gene U6 spliceosomal RNA Neighboring gene myo-inositol oxygenase Neighboring gene non-SMC condensin II complex, subunit H2 Neighboring gene thymidine phosphorylase Neighboring gene ciliary microtubule associated protein 1B

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General protein information

    Preferred Names
    lipase maturation factor 2
    Names
    transmembrane protein 112B

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001079939.1NP_001073408.1  lipase maturation factor 2

      See identical proteins and their annotated locations for NP_001073408.1

      Status: PROVISIONAL

      Source sequence(s)
      BC129102
      UniProtKB/Swiss-Prot
      A1L1J9, Q5I0G9
      Related
      ENSRNOP00000101764.1, ENSRNOT00000049538.5
      Conserved Domains (1) summary
      pfam06762
      Location:127587
      LMF1; Lipase maturation factor

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086025.1 Reference GRCr8

      Range
      122297971..122302423 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)