HLA-DQB2 major histocompatibility complex, class II, DQ beta 2 [Homo sapiens (human)] - Gene

Summary

Official Symbol: HLA-DQB2provided by HGNC
Official Full Name: major histocompatibility complex, class II, DQ beta 2provided by HGNC
Primary source: HGNC:HGNC:4945
See related: Ensembl:ENSG00000232629 MIM:615161; AllianceGenome:HGNC:4945
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Homo sapiens
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as: DQB2; HLA-DXB; HLA-DQB1
Summary: HLA-DQB2 belongs to the family of HLA class II beta chain paralogs. Class II molecules are heterodimers consisting of an alpha (DQA) and a beta chain (DQB), both anchored in the membrane. They play a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). Polymorphisms in the alpha and beta chains specify the peptide binding specificity, and typing for these polymorphisms is routinely done for bone marrow transplantation. However this gene, HLA-DQB2, is not routinely typed, as it is not thought to have an effect on transplantation. There is conflicting evidence in the literature and public sequence databases for the protein-coding capacity of HLA-DQB2. Because there is evidence of transcription and an intact ORF, HLA-DQB2 is represented in Entrez Gene and in RefSeq as a protein-coding locus. [provided by RefSeq, Oct 2010]
Expression: Biased expression in skin (RPKM 22.8), lung (RPKM 10.9) and 4 other tissues See more
Orthologs: all
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Genomic context

Location:: 6p21.32

Exon count:: 6

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCh38.p14 (GCF_000001405.40)	6	NC_000006.12 (32756098..32763532, complement)
RS_2024_08	current	T2T-CHM13v2.0 (GCF_009914755.1)	6	NC_060930.1 (32578824..32586261, complement)
RS_2024_09	previous assembly	GRCh37.p13 (GCF_000001405.25)	6	NC_000006.11 (32723875..32731309, complement)

Chromosome 6 - NC_000006.12 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: HPA RNA-seq normal tissues
Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
BioProject: PRJEB4337
Publication: PMID 24309898
Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

The functional HLA-DQB2 rs7453920 G>A polymorphism may contribute to the genetic susceptibility to pulmonary tuberculosis in the Chinese Uygur population.
Title: Association of human leukocyte antigens-DQB2/DPA1/DPB1 polymorphism and pulmonary tuberculosis in the Chinese Uygur population.
No statistically significant association was found between rs7453920 SNP and chronic hepatitis B.
Title: Lack of association between human leukocyte antigen polymorphisms rs9277535 and rs7453920 and chronic hepatitis B in a Brazilian population.
this study shows that HLA-DQ gene polymorphisms are associated with ankylosing spondylitis in Southwest China
Title: Association of HLA-DP/DQ and STAT4 polymorphisms with ankylosing spondylitis in Southwest China.
HLA-DQA2 and HLA-DQB2 genes are expressed in human Langerhans cells and encode a new HLA class II molecule.
Title: HLA-DQA2 and HLA-DQB2 genes are specifically expressed in human Langerhans cells and encode a new HLA class II molecule.
Data show that two peptides with naturally processed DQ8 (DQA1 *0301/DQB1 *0302) epitopes bound protective DR0403 with longer half-life and lower dissociation rate than susceptible DR0401, confirming DR0403 as a better peptide competitor than DR0401.
Title: Differences in self-peptide binding between T1D-related susceptible and protective DR4 subtypes.
Observational study of gene-disease association. (HuGE Navigator)
Title: Examination of genetic polymorphisms in newborns for signatures of sex-specific prenatal selection.

Submit: New GeneRIF Correction

Phenotypes

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Find tests for this gene in the NIH Genetic Testing Registry (GTR)

Review eQTL and phenotype association data in this region using PheGenI

EBI GWAS Catalog

Description
A genome-wide association study identified new variants associated with the risk of chronic hepatitis B. EBI GWAS Catalog EBI GWAS CatalogPubMed
A genome-wide association study identifies three new risk loci for Kawasaki disease. EBI GWAS Catalog EBI GWAS CatalogPubMed
A genome-wide association study of chronic hepatitis B identified novel risk locus in a Japanese population. EBI GWAS Catalog EBI GWAS CatalogPubMed
A genome-wide association study on chronic HBV infection and its clinical progression in male Han-Taiwanese. EBI GWAS Catalog EBI GWAS CatalogPubMed
Differential genetic associations for systemic lupus erythematosus based on anti-dsDNA autoantibody production. EBI GWAS Catalog EBI GWAS CatalogPubMed
Genome-wide pathway analysis of genome-wide association studies on systemic lupus erythematosus and rheumatoid arthritis. EBI GWAS Catalog EBI GWAS CatalogPubMed
Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. EBI GWAS Catalog EBI GWAS CatalogPubMed
New loci associated with chronic hepatitis B virus infection in Han Chinese. EBI GWAS Catalog EBI GWAS CatalogPubMed
Susceptibility loci associated with specific and shared subtypes of lymphoid malignancies. EBI GWAS Catalog EBI GWAS CatalogPubMed

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

HIV-1 interactions

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Protein interactions

Protein	Gene	Interaction	Pubs
Envelope surface glycoprotein gp120	env	HIV envelope protein gp120 can specifically inhibit CD4-dependent class II MHC-restricted T cell response to Ag	PubMed
	env	Amino acid residues 42-49 in the V1 region of CD4 are involved in the interaction between HIV-1 gp120 and class II major histocompatibility complex molecules	PubMed
Envelope surface glycoprotein gp160, precursor	env	Processing of HIV-1 gp160 to gp120 and gp41 is necessary for the association of HIV-1 envelope glycoproteins with class II MHC	PubMed
Envelope transmembrane glycoprotein gp41	env	A 43-amino-acid sequence between amino acids 708 and 750 in the HIV-1 gp41(TM) cytoplasmic tail is required for efficient incorporation of HLA class II proteins into virions	PubMed
	env	Soluble HIV-1 gp41 can selectively enhance MHC class I and II expression on human B cells, but does not increase expression of other cell surface antigens such as CD21 and CD54 (ICAM-1)	PubMed
	env	Soluble HIV-1 gp41 enhancement effects on MHC class I and II antigen expression can be inhibited by soluble gp41-binding proteins of 45, 49 and 62 kD from human B cells	PubMed
Nef	nef	Expression of patient-derived HIV-1 nef alleles downregulates MHC-II cell surface expression in activated CD4+ T cells	PubMed
	nef	HIV-1 group N and group O Nef alleles only weakly downregulate CD4, CD28, and class I and II MHC molecules	PubMed
	nef	HIV-1 Nef expression inhibits MHC II presentation of viral antigens in infected antigen-presenting cells	PubMed
	nef	Nef-triggered MHCII endocytosis requires Rab5 activity and lyst function, whereas lysosomal trafficking of internalized MHCII molecules requires Rab7 activity	PubMed
Pr55(Gag)	gag	HIV-1 Gag virus-like particles efficiently activate human monocyte-derived dendritic cells (MDDC) and induce MDDC maturation with an associated increase in the surface expression of CD80, CD86 and MHC classes I and II	PubMed
	gag	Two peptides of the CA domain of HIV-1 Gag, VDRFYKTLRAEQASQ and DRFYKLTRAEQASQ, are presented on MHC II molecules of dendritic cells and have similar sensitivity for antigen-specific T cells	PubMed
	gag	HIV-1 Gag virus-like particle-induced monocyte activation is shown by upregulation of molecules involved in antigen presentation (MHC II, CD80, CD86) and cell adhesion (CD54)	PubMed
Tat	tat	HIV-1 Tat downregulates expression of MHC class II genes in antigen-presenting cells (APC) by inhibiting the transactivator of MHC class II genes, CIITA	PubMed
Vpu	vpu	HIV-1 Vpu interacts with CD74 and modulates MHC II in HIV-1-infected cells	PubMed

Go to the HIV-1, Human Interaction Database

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

G43554 (e-PCR)
- UniSTS:95008

RH36565 (e-PCR)
- UniSTS:79192

RH46826 (e-PCR)
- UniSTS:57027

WI-16883 (e-PCR)
- UniSTS:55792

Gene Ontology Provided by GOA

Function	Evidence Code	Pubs
enables MHC class II protein complex binding	IBA Inferred from Biological aspect of Ancestor more info
enables MHC class II receptor activity	NAS Non-traceable Author Statement more info	PubMed
enables peptide antigen binding	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in adaptive immune response	IEA Inferred from Electronic Annotation more info
involved_in antigen processing and presentation of exogenous peptide antigen via MHC class II	IBA Inferred from Biological aspect of Ancestor more info
involved_in immune response	NAS Non-traceable Author Statement more info	PubMed
involved_in peptide antigen assembly with MHC class II protein complex	IBA Inferred from Biological aspect of Ancestor more info
involved_in positive regulation of T cell activation	IBA Inferred from Biological aspect of Ancestor more info
involved_in positive regulation of immune response	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
located_in ER to Golgi transport vesicle membrane	TAS Traceable Author Statement more info
located_in Golgi membrane	TAS Traceable Author Statement more info
part_of MHC class II protein complex	IBA Inferred from Biological aspect of Ancestor more info
part_of MHC class II protein complex	NAS Non-traceable Author Statement more info	PubMed
located_in clathrin-coated endocytic vesicle membrane	TAS Traceable Author Statement more info
located_in endocytic vesicle membrane	TAS Traceable Author Statement more info
is_active_in late endosome membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in lumenal side of endoplasmic reticulum membrane	TAS Traceable Author Statement more info
is_active_in lysosomal membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in lysosomal membrane	TAS Traceable Author Statement more info
located_in plasma membrane	TAS Traceable Author Statement more info
located_in trans-Golgi network membrane	TAS Traceable Author Statement more info
located_in transport vesicle membrane	TAS Traceable Author Statement more info

General protein information

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Preferred Names: HLA class II histocompatibility antigen, DQ beta 2 chain

Names: DV19.1 (major histocompatibility complex, class II, DQ beta 2 (HLA-DXB)); HLA class II histocompatibility antigen, DX beta chain; MHC class II antigen DQB2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001198858.2 → NP_001185787.1 HLA class II histocompatibility antigen, DQ beta 2 chain isoform 2 precursor

Status: REVIEWED

Description

Transcript Variant: This variant (2) lacks an in-frame exon in the 3' coding region, compared to variant 1. It encodes a shorter isoform (2), compared to isoform 1.

Source sequence(s)

AL672104

Consensus CDS

CCDS56419.1

UniProtKB/TrEMBL

Q5SQ91, Q8MGQ8

Related

ENSP00000390431.1, ENST00000411527.5

Conserved Domains (3) summary

cd05766
Location:124 → 217

IgC_MHC_II_beta; Class II major histocompatibility complex (MHC) beta chain immunoglobulin domain

smart00410
Location:142 → 214

IG_like; Immunoglobulin like

pfam00969
Location:41 → 111

MHC_II_beta; Class II histocompatibility antigen, beta domain
NM_001300790.2 → NP_001287719.1 HLA class II histocompatibility antigen, DQ beta 2 chain isoform 1 precursor

Status: REVIEWED

Description

Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).

Source sequence(s)

AL672104

Consensus CDS

CCDS78128.1

UniProtKB/Swiss-Prot

A6NIA5, P05538, Q29826, Q29870, Q29871, Q29872, Q29873, Q5SR06

UniProtKB/TrEMBL

Q5SR05

Related

ENSP00000396330.2, ENST00000437316.7

Conserved Domains (3) summary

cd05766
Location:124 → 217

IgC_MHC_II_beta; Class II major histocompatibility complex (MHC) beta chain immunoglobulin domain

smart00410
Location:142 → 214

IG_like; Immunoglobulin like

pfam00969
Location:41 → 111

MHC_II_beta; Class II histocompatibility antigen, beta domain

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

NC_000006.12 Reference GRCh38.p14 Primary Assembly

Range

32756098..32763532 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_011514561.4 → XP_011512863.1 HLA class II histocompatibility antigen, DQ beta 2 chain isoform X3

See identical proteins and their annotated locations for XP_011512863.1

UniProtKB/TrEMBL

A0A2H4Z4R5, A0A2H4Z4T8, A0A3B1EVN7

Related

ENSP00000415997.1, ENST00000427449.1

Conserved Domains (2) summary

cd05766
Location:124 → 216

IgC_MHC_II_beta; Class II major histocompatibility complex (MHC) beta chain immunoglobulin domain

pfam00969
Location:41 → 111

MHC_II_beta; Class II histocompatibility antigen, beta domain
XM_011514560.3 → XP_011512862.1 HLA class II histocompatibility antigen, DQ beta 2 chain isoform X2

See identical proteins and their annotated locations for XP_011512862.1

UniProtKB/Swiss-Prot

A6NIA5, P05538, Q29826, Q29870, Q29871, Q29872, Q29873, Q5SR06

Conserved Domains (3) summary

cd05766
Location:124 → 217

IgC_MHC_II_beta; Class II major histocompatibility complex (MHC) beta chain immunoglobulin domain

smart00410
Location:142 → 214

IG_like; Immunoglobulin like

pfam00969
Location:41 → 111

MHC_II_beta; Class II histocompatibility antigen, beta domain
XM_005249051.5 → XP_005249108.1 HLA class II histocompatibility antigen, DQ beta 2 chain isoform X1

See identical proteins and their annotated locations for XP_005249108.1

UniProtKB/Swiss-Prot

A6NIA5, P05538, Q29826, Q29870, Q29871, Q29872, Q29873, Q5SR06

UniProtKB/TrEMBL

A2ADX3

Related

ENSP00000410512.2, ENST00000435145.6

Conserved Domains (3) summary

cd05766
Location:124 → 217

IgC_MHC_II_beta; Class II major histocompatibility complex (MHC) beta chain immunoglobulin domain

smart00410
Location:142 → 214

IG_like; Immunoglobulin like

pfam00969
Location:41 → 111

MHC_II_beta; Class II histocompatibility antigen, beta domain

Reference GRCh38.p14 ALT_REF_LOCI_1

Genomic

NT_167244.2 Reference GRCh38.p14 ALT_REF_LOCI_1

Range

4062237..4069672 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_054328498.1 → XP_054184473.1 HLA class II histocompatibility antigen, DQ beta 2 chain isoform X3

UniProtKB/TrEMBL

A0A2H4Z4R5, A0A2H4Z4T8, A0A3B1EVN7
XM_054328497.1 → XP_054184472.1 HLA class II histocompatibility antigen, DQ beta 2 chain isoform X2

UniProtKB/Swiss-Prot

A6NIA5, P05538, Q29826, Q29870, Q29871, Q29872, Q29873, Q5SR06
XM_054328496.1 → XP_054184471.1 HLA class II histocompatibility antigen, DQ beta 2 chain isoform X1

UniProtKB/Swiss-Prot

A6NIA5, P05538, Q29826, Q29870, Q29871, Q29872, Q29873, Q5SR06

UniProtKB/TrEMBL

A2ADX3

Reference GRCh38.p14 ALT_REF_LOCI_2

Genomic

NT_113891.3 Reference GRCh38.p14 ALT_REF_LOCI_2

Range

4169671..4177106 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_054329805.1 → XP_054185780.1 HLA class II histocompatibility antigen, DQ beta 2 chain isoform X3

UniProtKB/TrEMBL

A0A2H4Z4R5, A0A2H4Z4T8, A0A3B1EVN7
XM_054329804.1 → XP_054185779.1 HLA class II histocompatibility antigen, DQ beta 2 chain isoform X2

UniProtKB/Swiss-Prot

A6NIA5, P05538, Q29826, Q29870, Q29871, Q29872, Q29873, Q5SR06
XM_054329803.1 → XP_054185778.1 HLA class II histocompatibility antigen, DQ beta 2 chain isoform X1

UniProtKB/Swiss-Prot

A6NIA5, P05538, Q29826, Q29870, Q29871, Q29872, Q29873, Q5SR06

UniProtKB/TrEMBL

A2ADX3

Reference GRCh38.p14 ALT_REF_LOCI_3

Genomic

NT_167245.2 Reference GRCh38.p14 ALT_REF_LOCI_3

Range

4000854..4008291 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_054330293.1 → XP_054186268.1 HLA class II histocompatibility antigen, DQ beta 2 chain isoform X7

UniProtKB/TrEMBL

A0A2H4Z4T8
XM_054330292.1 → XP_054186267.1 HLA class II histocompatibility antigen, DQ beta 2 chain isoform X6

UniProtKB/Swiss-Prot

A6NIA5, P05538, Q29826, Q29870, Q29871, Q29872, Q29873, Q5SR06
XM_054330290.1 → XP_054186265.1 HLA class II histocompatibility antigen, DQ beta 2 chain isoform X4

UniProtKB/Swiss-Prot

A6NIA5, P05538, Q29826, Q29870, Q29871, Q29872, Q29873, Q5SR06

UniProtKB/TrEMBL

A0A0G2JH31
XM_054330291.1 → XP_054186266.1 HLA class II histocompatibility antigen, DQ beta 2 chain isoform X5

UniProtKB/Swiss-Prot

A6NIA5, P05538, Q29826, Q29870, Q29871, Q29872, Q29873, Q5SR06

Reference GRCh38.p14 ALT_REF_LOCI_4

Genomic

NT_167246.2 Reference GRCh38.p14 ALT_REF_LOCI_4

Range

4175450..4182887 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_054330584.1 → XP_054186559.1 HLA class II histocompatibility antigen, DQ beta 2 chain isoform X11

UniProtKB/TrEMBL

A0A2H4Z4T8
XM_054330583.1 → XP_054186558.1 HLA class II histocompatibility antigen, DQ beta 2 chain isoform X10

UniProtKB/Swiss-Prot

A6NIA5, P05538, Q29826, Q29870, Q29871, Q29872, Q29873, Q5SR06
XM_054330581.1 → XP_054186556.1 HLA class II histocompatibility antigen, DQ beta 2 chain isoform X8

UniProtKB/Swiss-Prot

A6NIA5, P05538, Q29826, Q29870, Q29871, Q29872, Q29873, Q5SR06

UniProtKB/TrEMBL

A0A0G2JH31
XM_054330582.1 → XP_054186557.1 HLA class II histocompatibility antigen, DQ beta 2 chain isoform X9

UniProtKB/Swiss-Prot

A6NIA5, P05538, Q29826, Q29870, Q29871, Q29872, Q29873, Q5SR06

Reference GRCh38.p14 ALT_REF_LOCI_5

Genomic

NT_167247.2 Reference GRCh38.p14 ALT_REF_LOCI_5

Range

4055473..4062910 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_054330812.1 → XP_054186787.1 HLA class II histocompatibility antigen, DQ beta 2 chain isoform X15

UniProtKB/TrEMBL

A0A2H4Z4T8
XM_054330811.1 → XP_054186786.1 HLA class II histocompatibility antigen, DQ beta 2 chain isoform X14

UniProtKB/Swiss-Prot

A6NIA5, P05538, Q29826, Q29870, Q29871, Q29872, Q29873, Q5SR06
XM_054330809.1 → XP_054186784.1 HLA class II histocompatibility antigen, DQ beta 2 chain isoform X12

UniProtKB/Swiss-Prot

A6NIA5, P05538, Q29826, Q29870, Q29871, Q29872, Q29873, Q5SR06

UniProtKB/TrEMBL

A0A0G2JH31
XM_054330810.1 → XP_054186785.1 HLA class II histocompatibility antigen, DQ beta 2 chain isoform X13

UniProtKB/Swiss-Prot

A6NIA5, P05538, Q29826, Q29870, Q29871, Q29872, Q29873, Q5SR06

Reference GRCh38.p14 ALT_REF_LOCI_6

Genomic

NT_167248.2 Reference GRCh38.p14 ALT_REF_LOCI_6

Range

3950399..3957836 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_054331060.1 → XP_054187035.1 HLA class II histocompatibility antigen, DQ beta 2 chain isoform X19

UniProtKB/TrEMBL

A0A2H4Z4T8
XM_054331059.1 → XP_054187034.1 HLA class II histocompatibility antigen, DQ beta 2 chain isoform X18

UniProtKB/Swiss-Prot

A6NIA5, P05538, Q29826, Q29870, Q29871, Q29872, Q29873, Q5SR06
XM_054331057.1 → XP_054187032.1 HLA class II histocompatibility antigen, DQ beta 2 chain isoform X16

UniProtKB/Swiss-Prot

A6NIA5, P05538, Q29826, Q29870, Q29871, Q29872, Q29873, Q5SR06

UniProtKB/TrEMBL

A0A0G2JH31
XM_054331058.1 → XP_054187033.1 HLA class II histocompatibility antigen, DQ beta 2 chain isoform X17

UniProtKB/Swiss-Prot

A6NIA5, P05538, Q29826, Q29870, Q29871, Q29872, Q29873, Q5SR06

Reference GRCh38.p14 ALT_REF_LOCI_7

Genomic

NT_167249.2 Reference GRCh38.p14 ALT_REF_LOCI_7

Range

4156243..4163677 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_054331324.1 → XP_054187299.1 HLA class II histocompatibility antigen, DQ beta 2 chain isoform X3

UniProtKB/TrEMBL

A0A2H4Z4R5, A0A2H4Z4T8, A0A3B1EVN7
XM_054331323.1 → XP_054187298.1 HLA class II histocompatibility antigen, DQ beta 2 chain isoform X2

UniProtKB/Swiss-Prot

A6NIA5, P05538, Q29826, Q29870, Q29871, Q29872, Q29873, Q5SR06
XM_054331322.1 → XP_054187297.1 HLA class II histocompatibility antigen, DQ beta 2 chain isoform X1

UniProtKB/Swiss-Prot

A6NIA5, P05538, Q29826, Q29870, Q29871, Q29872, Q29873, Q5SR06

UniProtKB/TrEMBL

A2ADX3

Alternate T2T-CHM13v2.0

Genomic

NC_060930.1 Alternate T2T-CHM13v2.0

Range

32578824..32586261 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_054355297.1 → XP_054211272.1 HLA class II histocompatibility antigen, DQ beta 2 chain isoform X23

UniProtKB/TrEMBL

A0A2H4Z4T8
XM_054355296.1 → XP_054211271.1 HLA class II histocompatibility antigen, DQ beta 2 chain isoform X22

UniProtKB/Swiss-Prot

A6NIA5, P05538, Q29826, Q29870, Q29871, Q29872, Q29873, Q5SR06
XM_054355294.1 → XP_054211269.1 HLA class II histocompatibility antigen, DQ beta 2 chain isoform X20

UniProtKB/Swiss-Prot

A6NIA5, P05538, Q29826, Q29870, Q29871, Q29872, Q29873, Q5SR06

UniProtKB/TrEMBL

A0A0G2JH31
XM_054355295.1 → XP_054211270.1 HLA class II histocompatibility antigen, DQ beta 2 chain isoform X21

UniProtKB/Swiss-Prot

A6NIA5, P05538, Q29826, Q29870, Q29871, Q29872, Q29873, Q5SR06

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

NM_182549.1: Suppressed sequence

Description

NM_182549.1: This RefSeq was permanently suppressed because it is now thought that this gene is a pseudogene.
NR_003937.1: Suppressed sequence

Description

NR_003937.1: This RefSeq was permanently suppressed because it is now thought that this gene does encode a protein.