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    Vmac vimentin-type intermediate filament associated coiled-coil protein [ Mus musculus (house mouse) ]

    Gene ID: 106639, updated on 9-Dec-2024

    Summary

    Official Symbol
    Vmacprovided by MGI
    Official Full Name
    vimentin-type intermediate filament associated coiled-coil proteinprovided by MGI
    Primary source
    MGI:MGI:2146912
    See related
    Ensembl:ENSMUSG00000054723 AllianceGenome:MGI:2146912
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Summary
    Predicted to be located in cytoplasm. Predicted to be active in type III intermediate filament. Orthologous to human VMAC (vimentin type intermediate filament associated coiled-coil protein). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in ovary adult (RPKM 20.2), adrenal adult (RPKM 18.8) and 27 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Vmac in Genome Data Viewer
    Location:
    17 D; 17 29.47 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (57020936..57024688, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (56713932..56717699, complement)

    Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene cation channel sperm associated auxiliary subunit delta Neighboring gene predicted gene, 33461 Neighboring gene STARR-seq mESC enhancer starr_42897 Neighboring gene RAN binding protein 3 Neighboring gene STARR-seq mESC enhancer starr_42898 Neighboring gene STARR-positive B cell enhancer ABC_E962 Neighboring gene calcyphosine, pseudogene Neighboring gene NADH:ubiquinone oxidoreductase subunit A11 Neighboring gene fucosyltransferase 4, pseudogene 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
     
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in type III intermediate filament IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in type III intermediate filament ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    vimentin-type intermediate filament-associated coiled-coil protein

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001166474.2NP_001159946.1  vimentin-type intermediate filament-associated coiled-coil protein isoform 2

      See identical proteins and their annotated locations for NP_001159946.1

      Status: VALIDATED

      Source sequence(s)
      CT010491
      Consensus CDS
      CCDS50154.1
      UniProtKB/TrEMBL
      G3XA49
      Related
      ENSMUSP00000132817.2, ENSMUST00000164907.3
    2. NM_178926.4NP_849257.1  vimentin-type intermediate filament-associated coiled-coil protein isoform 1

      See identical proteins and their annotated locations for NP_849257.1

      Status: VALIDATED

      Source sequence(s)
      CT010491
      Consensus CDS
      CCDS28912.1
      UniProtKB/Swiss-Prot
      Q3UKV2, Q8BP01
      Related
      ENSMUSP00000064120.6, ENSMUST00000067931.7
      Conserved Domains (1) summary
      pfam15272
      Location:35113
      BBP1_C; Spindle pole body component BBP1, C-terminal

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000083.7 Reference GRCm39 C57BL/6J

      Range
      57020936..57024688 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)