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    sfh1 RSC complex subunit Sfh1 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2539144, updated on 18-Sep-2024

    Summary

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    Official Symbol
    sfh1
    Official Full Name
    RSC complex subunit Sfh1
    Primary source
    PomBase:SPCC16A11.14
    Locus tag
    SPOM_SPCC16A11.14
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See sfh1 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    1
    Sequence:
    Chromosome: III; NC_003421.2 (894153..895679)

    Chromosome III - NC_003421.2Genomic Context describing neighboring genes Neighboring gene ubiquitin hydrolase Ubp1 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene U1 snRNP-associated protein Luc7 Neighboring gene uncharacterized protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003421.2

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Sfh1, an essential component of the RSC chromatin remodeling complex, maintains genome integrity in fission yeast. Kotomura N, et al. Genes Cells, 2018 Sep. PMID 30155942
    2. The chromatin remodeler RSC prevents ectopic CENP-A propagation into pericentromeric heterochromatin at the chromatin boundary. Tsunemine S, et al. Nucleic Acids Res, 2022 Oct 28. PMID 36200823, Free PMC Article
    3. Fission yeast SWI/SNF and RSC complexes show compositional and functional differences from budding yeast. Monahan BJ, et al. Nat Struct Mol Biol, 2008 Aug. PMID 18622392, Free PMC Article
    4. Two-hybrid search for proteins that interact with Sad1 and Kms1, two membrane-bound components of the spindle pole body in fission yeast. Miki F, et al. Mol Genet Genomics, 2004 Jan. PMID 14655046
    5. A large complex mediated by Moc1, Moc2 and Cpc2 regulates sexual differentiation in fission yeast. Paul SK, et al. FEBS J, 2009 Sep. PMID 19682301

    See all (14) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables transcription coregulator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in chromatin remodeling IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in heterochromatin boundary formation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in transcription initiation-coupled chromatin remodeling IC
    Inferred by Curator
    more info
    		  
    Component Evidence Code Pubs
    part_of RSC-type complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of RSC-type complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in cytosol HDA PubMed 
    is_active_in nuclear chromosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in nucleus HDA PubMed 
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    RSC complex subunit Sfh1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003421.2 Reference assembly

      Range
      894153..895679
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001022992.3 → NP_588001.1  RSC complex subunit Sfh1 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_588001.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      Q9USM3
      Conserved Domains (2) summary
      pfam00320
      Location:372 → 409
      GATA; GATA zinc finger
      pfam04855
      Location:118 → 261
      SNF5; SNF5 / SMARCB1 / INI1
    Nucleotide Protein
    Heading Accession and Version

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