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    srp54 signal recognition particle subunit Srp54 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2539290, updated on 18-Sep-2024

    Summary

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    Official Symbol
    srp54
    Official Full Name
    signal recognition particle subunit Srp54
    Primary source
    PomBase:SPCC188.06c
    Locus tag
    SPOM_SPCC188.06C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See srp54 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    2
    Sequence:
    Chromosome: III; NC_003421.2 (1482990..1485200, complement)

    Chromosome III - NC_003421.2Genomic Context describing neighboring genes Neighboring gene Ndc80 complex subunit Spc25 Neighboring gene condensin complex non-SMC subunit Cnd3 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene shelterin complex HEAT repeat subunit Ccq1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003421.2

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Identification of RNA sequences and structural elements required for assembly of fission yeast SRP54 protein with signal recognition particle RNA. Selinger D, et al. Mol Cell Biol, 1993 Mar. PMID 8382769, Free PMC Article
    2. The Srp54 GTPase is essential for protein export in the fission yeast Schizosaccharomyces pombe. Althoff SM, et al. Mol Cell Biol, 1994 Dec. PMID 7969124, Free PMC Article
    3. Genetic and biochemical analysis of the fission yeast ribonucleoprotein particle containing a homolog of Srp54p. Selinger D, et al. Nucleic Acids Res, 1994 Jul 11. PMID 8041618, Free PMC Article
    4. A large complex mediated by Moc1, Moc2 and Cpc2 regulates sexual differentiation in fission yeast. Paul SK, et al. FEBS J, 2009 Sep. PMID 19682301
    5. Proximity-dependent biotinylation mediated by TurboID to identify protein-protein interaction networks in yeast. Larochelle M, et al. J Cell Sci, 2019 May 31. PMID 31064814

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables 7S RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables 7S RNA binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables ATP hydrolysis activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables GTP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables GTPase activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    enables endoplasmic reticulum signal peptide binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in SRP-dependent cotranslational protein targeting to membrane IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in SRP-dependent cotranslational protein targeting to membrane, translocation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytosol HDA PubMed 
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in endoplasmic reticulum HDA PubMed 
    part_of signal recognition particle, endoplasmic reticulum targeting IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of signal recognition particle, endoplasmic reticulum targeting IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    signal recognition particle subunit Srp54

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003421.2 Reference assembly

      Range
      1482990..1485200 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001023199.3 → NP_588209.1  signal recognition particle subunit Srp54 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_588209.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      P21565
      Conserved Domains (4) summary
      TIGR01425
      Location:2 → 426
      SRP54_euk; signal recognition particle protein SRP54
      pfam00448
      Location:102 → 293
      SRP54; SRP54-type protein, GTPase domain
      pfam02881
      Location:6 → 83
      SRP54_N; SRP54-type protein, helical bundle domain
      pfam02978
      Location:325 → 428
      SRP_SPB; Signal peptide binding domain
    Nucleotide Protein
    Heading Accession and Version

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