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    arg12 argininosuccinate synthase [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2541050, updated on 18-Sep-2024

    Summary

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    Official Symbol
    arg12
    Official Full Name
    argininosuccinate synthase
    Primary source
    PomBase:SPBC428.05c
    Locus tag
    SPOM_SPBC428.05C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See arg12 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    1
    Sequence:
    Chromosome: II; NC_003423.3 (449440..451025, complement)

    Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene nuclear membrane organization protein Apq12 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Clr6 and Rpd3L histone deacetylase complex subunit Rxt2 Neighboring gene ncRNA Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003423.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Development of a genetic transformation system using new selectable markers for fission yeast Schizosaccharomyces pombe. Fujita Y, et al. Yeast, 2005 Feb. PMID 15704224
    2. Mitochondrial respiration is required to provide amino acids during fermentative proliferation of fission yeast. Malecki M, et al. EMBO Rep, 2020 Nov 5. PMID 32896087, Free PMC Article
    3. The fission yeast FLCN/FNIP complex augments TORC1 repression or activation in response to amino acid (AA) availability. Calvo IA, et al. iScience, 2021 Nov 19. PMID 34805795, Free PMC Article
    4. A Two-step Protein Quality Control Pathway for a Misfolded DJ-1 Variant in Fission Yeast. Mathiassen SG, et al. J Biol Chem, 2015 Aug 21. PMID 26152728, Free PMC Article
    5. Cross-species protein interactome mapping reveals species-specific wiring of stress response pathways. Das J, et al. Sci Signal, 2013 May 21. PMID 23695164, Free PMC Article

    See all (20) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables argininosuccinate synthase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables argininosuccinate synthase activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in L-arginine biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in L-arginine biosynthetic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in arginine biosynthetic process via ornithine EXP
    Inferred from Experiment
    more info
    		 PubMed 
    involved_in argininosuccinate metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in urea cycle IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in cytosol HDA PubMed 

    General protein information

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    Preferred Names
    argininosuccinate synthase

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003423.3 Reference assembly

      Range
      449440..451025 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001021091.3 → NP_595183.1  argininosuccinate synthase [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_595183.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O94354
      Conserved Domains (1) summary
      COG0137
      Location:2 → 410
      ArgG; Argininosuccinate synthase [Amino acid transport and metabolism]
    Nucleotide Protein
    Heading Accession and Version

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