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    sam1 S-adenosylmethionine synthetase [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2539943, updated on 18-Sep-2024

    Summary

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    Official Symbol
    sam1
    Official Full Name
    S-adenosylmethionine synthetase
    Primary source
    PomBase:SPBC14F5.05c
    Locus tag
    SPOM_SPBC14F5.05C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See sam1 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    1
    Sequence:
    Chromosome: II; NC_003423.3 (4162069..4163858, complement)

    Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene 5S ribosomal RNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Fe-sulfur ATPase Rli1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003423.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Gene sam1 encoding adenosylmethionine synthetase: effects of its expression in the fission yeast Schizosaccharomyces pombe. Hilti N, et al. Yeast, 2000 Jan 15. PMID 10620770
    2. Interaction between a negative regulator (Msa2/Nrd1) and a positive regulator (Cpc2) of sexual differentiation in Schizosaccharomyces pombe. Jeong HT, et al. Biosci Biotechnol Biochem, 2004 Jul. PMID 15277777
    3. Proteome-wide search for PP2A substrates in fission yeast. Bernal M, et al. Proteomics, 2014 Jun. PMID 24634168
    4. Cross-species protein interactome mapping reveals species-specific wiring of stress response pathways. Das J, et al. Sci Signal, 2013 May 21. PMID 23695164, Free PMC Article
    5. Characterization of Mug33 reveals complementary roles for actin cable-dependent transport and exocyst regulators in fission yeast exocytosis. Snaith HA, et al. J Cell Sci, 2011 Jul 1. PMID 21652630, Free PMC Article

    See all (19) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables ATP binding ISM
    Inferred from Sequence Model
    more info
    		  
    enables methionine adenosyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables methionine adenosyltransferase activity IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in S-adenosylmethionine biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in methionine metabolic process IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in cytosol HDA PubMed 
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in nucleus HDA PubMed 

    General protein information

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    Preferred Names
    S-adenosylmethionine synthetase

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003423.3 Reference assembly

      Range
      4162069..4163858 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001022657.3 → NP_596731.1  S-adenosylmethionine synthetase [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_596731.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O60198
      Conserved Domains (4) summary
      PTZ00104
      Location:1 → 381
      PTZ00104; S-adenosylmethionine synthase; Provisional
      pfam00438
      Location:4 → 101
      S-AdoMet_synt_N; S-adenosylmethionine synthetase, N-terminal domain
      pfam02772
      Location:116 → 237
      S-AdoMet_synt_M; S-adenosylmethionine synthetase, central domain
      pfam02773
      Location:239 → 375
      S-AdoMet_synt_C; S-adenosylmethionine synthetase, C-terminal domain
    Nucleotide Protein
    Heading Accession and Version

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