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    rec11 meiotic cohesin complex STAG protein Rec11 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2538852, updated on 18-Sep-2024

    Summary

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    Official Symbol
    rec11
    Official Full Name
    meiotic cohesin complex STAG protein Rec11
    Primary source
    PomBase:SPCC4E9.01c
    Locus tag
    SPOM_SPCC4E9.01C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    Also known as
    SPCC550.16c
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    Genomic context

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    See rec11 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    9
    Sequence:
    Chromosome: III; NC_003421.2 (1223308..1226968, complement)

    Chromosome III - NC_003421.2Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ribosome biogenesis protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene G1/S-specific B-type cyclin Cig1 Neighboring gene cardiolipin synthase PGP phosphatase domain-containing Gep4

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003421.2

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Cohesin and recombination proteins influence the G1-to-S transition in azygotic meiosis in Schizosaccharomyces pombe. Doll E, et al. Genetics, 2008 Oct. PMID 18780734, Free PMC Article
    2. Distinct cohesin complexes organize meiotic chromosome domains. Kitajima TS, et al. Science, 2003 May 16. PMID 12750522
    3. Novel genes required for meiotic chromosome segregation are identified by a high-throughput knockout screen in fission yeast. Gregan J, et al. Curr Biol, 2005 Sep 20. PMID 16169489
    4. Casein Kinase 1 and Phosphorylation of Cohesin Subunit Rec11 (SA3) Promote Meiotic Recombination through Linear Element Formation. Phadnis N, et al. PLoS Genet, 2015 May. PMID 25993311, Free PMC Article
    5. Repositioning of aurora B promoted by chiasmata ensures sister chromatid mono-orientation in meiosis I. Sakuno T, et al. Dev Cell, 2011 Sep 13. PMID 21920317

    See all (16) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. These observations suggest wide-spread conservation of the roles of casein kinase 1 and Rec11 in ensuring proper meiotic chromosome segregation and sexual reproduction.
      Title: Casein Kinase 1 and Phosphorylation of Cohesin Subunit Rec11 (SA3) Promote Meiotic Recombination through Linear Element Formation.
    2. expression of Rec11-Rec10 fusion protein nearly completely bypasses the requirement for casein kinase 1 or cohesin phosphorylation for LinE assembly and recombination
      Title: Phosphorylation of cohesin Rec11/SA3 by casein kinase 1 promotes homologous recombination by assembling the meiotic chromosome axis.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables chromatin binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    contributes_to topological DNA co-entrapment activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in homologous chromosome orientation in meiotic metaphase I IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in linear element assembly IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in meiotic sister chromatid cohesion IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in meiotic sister chromatid cohesion involved in meiosis I IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in sister chromatid cohesion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in chromatin IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in chromatin IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of cohesin complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of meiotic cohesin complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in nucleus HDA PubMed 
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    meiotic cohesin complex STAG protein Rec11

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003421.2 Reference assembly

      Range
      1223308..1226968 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001023099.4 → NP_588108.3  meiotic cohesin complex STAG protein Rec11 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_588108.3

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      Q7LL03, Q92380, Q9USJ0
      Conserved Domains (2) summary
      COG5537
      Location:2 → 766
      IRR1; Cohesin [Cell division and chromosome partitioning]
      pfam08514
      Location:165 → 253
      STAG; STAG domain
    Nucleotide Protein
    Heading Accession and Version

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