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    lys9 saccharopine dehydrogenase [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2540908, updated on 18-Sep-2024

    Summary

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    Official Symbol
    lys9
    Official Full Name
    saccharopine dehydrogenase
    Primary source
    PomBase:SPBC3B8.03
    Locus tag
    SPOM_SPBC3B8.03
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See lys9 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    1
    Sequence:
    Chromosome: II; NC_003423.3 (3391684..3393229, complement)

    Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene phosphate transporter Neighboring gene ncRNA Neighboring gene mitochondrial F1-FO ATP synthase peripheral stalk assembly factor Ina17 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene CCAAT-binding factor complex histone fold subunit Php5

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003423.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Global fitness profiling of fission yeast deletion strains by barcode sequencing. Han TX, et al. Genome Biol, 2010. PMID 20537132, Free PMC Article
    2. CPF-associated phosphatase activity opposes condensin-mediated chromosome condensation. Vanoosthuyse V, et al. PLoS Genet, 2014 Jun. PMID 24945319, Free PMC Article
    3. Posttranslational Arginylation Enzyme Arginyltransferase1 Shows Genetic Interactions With Specific Cellular Pathways in vivo. Wiley DJ, et al. Front Physiol, 2020. PMID 32435206, Free PMC Article
    4. Characterization of Mug33 reveals complementary roles for actin cable-dependent transport and exocyst regulators in fission yeast exocytosis. Snaith HA, et al. J Cell Sci, 2011 Jul 1. PMID 21652630, Free PMC Article
    5. A genetic screen to discover pathways affecting cohesin function in Schizosaccharomyces pombe identifies chromatin effectors. Chen Z, et al. G3 (Bethesda), 2012 Oct. PMID 23050226, Free PMC Article

    See all (15) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables saccharopine dehydrogenase (NADP+, L-glutamate-forming) activity ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables saccharopine dehydrogenase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in lysine biosynthetic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in lysine biosynthetic process via aminoadipic acid IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in cytosol HDA PubMed 

    General protein information

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    Preferred Names
    saccharopine dehydrogenase

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003423.3 Reference assembly

      Range
      3391684..3393229 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001022330.3 → NP_596411.1  saccharopine dehydrogenase [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_596411.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O59711
      Conserved Domains (3) summary
      COG1748
      Location:1 → 396
      Lys9; Saccharopine dehydrogenase, NADP-dependent [Amino acid transport and metabolism]
      pfam03435
      Location:4 → 119
      Sacchrp_dh_NADP; Saccharopine dehydrogenase NADP binding domain
      pfam16653
      Location:123 → 439
      Sacchrp_dh_C; Saccharopine dehydrogenase C-terminal domain
    Nucleotide Protein
    Heading Accession and Version

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