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    xan1 alpha-ketoglutarate-dependent xanthine dioxygenase Xan1 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2539549, updated on 18-Sep-2024

    Summary

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    Official Symbol
    xan1
    Official Full Name
    alpha-ketoglutarate-dependent xanthine dioxygenase Xan1
    Primary source
    PomBase:SPCC576.01c
    Locus tag
    SPOM_SPCC576.01C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    Also known as
    SPCPB1C11.04c
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    Genomic context

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    See xan1 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    1
    Sequence:
    Chromosome: III; NC_003421.2 (2079421..2080662, complement)

    Chromosome III - NC_003421.2Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene cysteine transporter Neighboring gene uncharacterized protein Neighboring gene hydantoin racemase family protein Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003421.2

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Convergent evolution of hydroxylation mechanisms in the fungal kingdom: molybdenum cofactor-independent hydroxylation of xanthine via alpha-ketoglutarate-dependent dioxygenases. Cultrone A, et al. Mol Microbiol, 2005 Jul. PMID 15948966
    2. The fission yeast nucleoporin Alm1 is required for proteasomal degradation of kinetochore components. Salas-Pino S, et al. J Cell Biol, 2017 Nov 6. PMID 28974540, Free PMC Article
    3. Hierarchical modularity and the evolution of genetic interactomes across species. Ryan CJ, et al. Mol Cell, 2012 Jun 8. PMID 22681890, Free PMC Article
    4. ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe. Matsuyama A, et al. Nat Biotechnol, 2006 Jul. PMID 16823372
    5. Transcription and RNA-processing in fission yeast mitochondria. Schäfer B, et al. RNA, 2005 May. PMID 15811919, Free PMC Article

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables alpha-ketoglutarate-dependent xanthine dioxygenase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables iron ion binding TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in xanthine catabolic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in cytosol HDA PubMed 
    is_active_in nucleus HDA PubMed 

    General protein information

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    Preferred Names
    alpha-ketoglutarate-dependent xanthine dioxygenase Xan1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003421.2 Reference assembly

      Range
      2079421..2080662 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001023418.1 → NP_588427.2  alpha-ketoglutarate-dependent xanthine dioxygenase Xan1 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_588427.2

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O74885, Q9C0U8
      Conserved Domains (2) summary
      COG2175
      Location:135 → 406
      TauD; Taurine dioxygenase, alpha-ketoglutarate-dependent [Secondary metabolites biosynthesis, transport and catabolism]
      pfam02668
      Location:49 → 394
      TauD; Taurine catabolism dioxygenase TauD, TfdA family
    Nucleotide Protein
    Heading Accession and Version

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