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    gar2 nucleolin [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2542869, updated on 18-Sep-2024

    Summary

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    Official Symbol
    gar2
    Official Full Name
    nucleolin
    Primary source
    PomBase:SPAC140.02
    Locus tag
    SPOM_SPAC140.02
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See gar2 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    1
    Sequence:
    Chromosome: I; NC_003424.3 (1897462..1899491)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene succinate dehydrogenase iron-sulfur subunit protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene argonaute inhibitor protein 1 Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Transcription-facilitating histone chaperons interact with genomic and synthetic G4 structures. Pavlova II, et al. Int J Biol Macromol, 2020 Oct 1. PMID 32454109
    2. Ultrastructural changes in the Schizosaccharomyces pombe nucleolus following the disruption of the gar2+ gene, which encodes a nucleolar protein structurally related to nucleolin. Léger-Silvestre I, et al. Chromosoma, 1997 Jun. PMID 9211982
    3. The role of the Schizosaccharomyces pombe gar2 protein in nucleolar structure and function depends on the concerted action of its highly charged N terminus and its RNA-binding domains. Sicard H, et al. Mol Biol Cell, 1998 Aug. PMID 9693363, Free PMC Article
    4. gar2 is a nucleolar protein from Schizosaccharomyces pombe required for 18S rRNA and 40S ribosomal subunit accumulation. Gulli MP, et al. Nucleic Acids Res, 1995 Jun 11. PMID 7596817, Free PMC Article
    5. Ccp1 modulates epigenetic stability at centromeres and affects heterochromatin distribution in Schizosaccharomyces pombe. Lu M, et al. J Biol Chem, 2018 Aug 3. PMID 29899117, Free PMC Article

    See all (30) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables RNA binding TAS
    Traceable Author Statement
    more info
    		 PubMed 
    enables histone chaperone activity TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in chromatin remodeling TAS
    Traceable Author Statement
    more info
    		 PubMed 
    involved_in rRNA metabolic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in rRNA processing IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in dense fibrillar component IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in nucleolus HDA PubMed 
    is_active_in nucleolus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    nucleolin

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      1897462..1899491
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001018965.3 → NP_593531.1  nucleolin [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_593531.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O13707, P41891
      Conserved Domains (2) summary
      cd12447
      Location:264 → 339
      RRM1_gar2; RNA recognition motif 1 in yeast protein gar2 and similar proteins
      cd12448
      Location:368 → 439
      RRM2_gar2; RNA recognition motif 2 in yeast protein gar2 and similar proteins
    Nucleotide Protein
    Heading Accession and Version

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