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    gmh5 alpha-1,2-galactosyltransferase [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2543384, updated on 18-Sep-2024

    Summary

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    Official Symbol
    gmh5
    Official Full Name
    alpha-1,2-galactosyltransferase
    Primary source
    PomBase:SPAC637.06
    Locus tag
    SPOM_SPAC637.06
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See gmh5 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    1
    Sequence:
    Chromosome: I; NC_003424.3 (4549790..4551242)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene cargo transport protein Ypp1 Neighboring gene ncRNA Neighboring gene V-type ATPase V1 subunit B Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene translation initiation factor eIF3d Neighboring gene ncRNA Neighboring gene Fe-sulfur cluster assembly ATPase Nbp35

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Structural analysis of α1,3-linked galactose-containing oligosaccharides in Schizosaccharomyces pombe mutants harboring single and multiple α-galactosyltransferase genes disruptions. Ohashi T, et al. Glycobiology, 2011 Mar. PMID 21098516
    2. Substrate specificities of α1,2- and α1,3-galactosyltransferases and characterization of Gmh1p and Otg1p in Schizosaccharomyces pombe. Fukunaga T, et al. Glycobiology, 2021 Sep 9. PMID 33909078
    3. Identification of novel α1,3-galactosyltransferase and elimination of α-galactose-containing glycans by disruption of multiple α-galactosyltransferase genes in Schizosaccharomyces pombe. Ohashi T, et al. J Biol Chem, 2012 Nov 9. PMID 22988247, Free PMC Article
    4. Significant conservation of synthetic lethal genetic interaction networks between distantly related eukaryotes. Dixon SJ, et al. Proc Natl Acad Sci U S A, 2008 Oct 28. PMID 18931302, Free PMC Article
    5. High-Throughput Identification of Nuclear Envelope Protein Interactions in Schizosaccharomyces pombe Using an Arrayed Membrane Yeast-Two Hybrid Library. Varberg JM, et al. G3 (Bethesda), 2020 Dec 3. PMID 33109728, Free PMC Article

    See all (15) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. an alpha1,2-galactosyltransferase-related gene was identified in the Schizosaccharomyces pombe genome and characterized [gmh5]
      Title: Structural analysis of α1,3-linked galactose-containing oligosaccharides in Schizosaccharomyces pombe mutants harboring single and multiple α-galactosyltransferase genes disruptions.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables alpha-1,2-galactosyltransferase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in protein N-linked glycosylation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in Golgi apparatus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in Golgi membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    alpha-1,2-galactosyltransferase

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      4549790..4551242
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001020052.3 → NP_594624.1  alpha-1,2-galactosyltransferase [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_594624.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      P78817, Q1L849
      Conserved Domains (1) summary
      pfam05637
      Location:71 → 323
      Glyco_transf_34; galactosyl transferase GMA12/MNN10 family
    Nucleotide Protein
    Heading Accession and Version

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