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    pep7 FYVE tethering component Pep7 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2542423, updated on 18-Sep-2024

    Summary

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    Official Symbol
    pep7
    Official Full Name
    FYVE tethering component Pep7
    Primary source
    PomBase:SPAC17G6.08
    Locus tag
    SPOM_SPAC17G6.08
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    Also known as
    vac1
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    Genomic context

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    See pep7 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    1
    Sequence:
    Chromosome: I; NC_003424.3 (3601717..3603904)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene SNARE protein Use1 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene translocation subcomplex subunit Sec62 Neighboring gene ncRNA Neighboring gene SWI/SNF and RSC complex subunit Ssr1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Yeast SREBP cleavage activation requires the Golgi Dsc E3 ligase complex. Stewart EV, et al. Mol Cell, 2011 Apr 22. PMID 21504829, Free PMC Article
    2. A Proteome-wide Fission Yeast Interactome Reveals Network Evolution Principles from Yeasts to Human. Vo TV, et al. Cell, 2016 Jan 14. PMID 26771498, Free PMC Article
    3. Hierarchical modularity and the evolution of genetic interactomes across species. Ryan CJ, et al. Mol Cell, 2012 Jun 8. PMID 22681890, Free PMC Article
    4. ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe. Matsuyama A, et al. Nat Biotechnol, 2006 Jul. PMID 16823372
    5. Transcription and RNA-processing in fission yeast mitochondria. Schäfer B, et al. RNA, 2005 May. PMID 15811919, Free PMC Article

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables phosphatidylinositol-3-phosphate binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    Process Evidence Code Pubs
    involved_in Golgi to vacuole transport ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in vesicle docking involved in exocytosis ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in vesicle fusion ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    is_active_in Golgi apparatus HDA PubMed 
    is_active_in cytoplasm HDA PubMed 
    is_active_in cytoplasmic side of endosome membrane ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    FYVE tethering component Pep7

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      3601717..3603904
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001019678.3 → NP_594255.1  FYVE tethering component Pep7 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_594255.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O13786
      Conserved Domains (3) summary
      smart00064
      Location:271 → 333
      FYVE; Protein present in Fab1, YOTB, Vac1, and EEA1
      cd15761
      Location:128 → 205
      FYVE1_Vac1p_like; FYVE-related domain 1 found in yeast protein VAC1 (Vac1p) and similar proteins
      pfam11464
      Location:483 → 522
      Rbsn; Rabenosyn Rab binding domain
    Nucleotide Protein
    Heading Accession and Version

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