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    ccp1 CENP-A histone disassembly chaperone Ccp1 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2540967, updated on 18-Sep-2024

    Summary

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    Official Symbol
    ccp1
    Official Full Name
    CENP-A histone disassembly chaperone Ccp1
    Primary source
    PomBase:SPBC36B7.08c
    Locus tag
    SPOM_SPBC36B7.08C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See ccp1 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    5
    Sequence:
    Chromosome: II; NC_003423.3 (2393472..2395581, complement)

    Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ubiquitin-protein ligase E/phosphatidylinositol(3)-phosphate binding protein Neighboring gene protein mug20 Neighboring gene SNARE protein Tgl1 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene eIF2 alpha kinase Gcn2 Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003423.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Ccp1 modulates epigenetic stability at centromeres and affects heterochromatin distribution in Schizosaccharomyces pombe. Lu M, et al. J Biol Chem, 2018 Aug 3. PMID 29899117, Free PMC Article
    2. Ccp1 Homodimer Mediates Chromatin Integrity by Antagonizing CENP-A Loading. Dong Q, et al. Mol Cell, 2016 Oct 6. PMID 27666591, Free PMC Article
    3. Ccp1-Ndc80 switch at the N terminus of CENP-T regulates kinetochore assembly. Dong Q, et al. Proc Natl Acad Sci U S A, 2021 Nov 30. PMID 34810257, Free PMC Article
    4. Promoter nucleosome dynamics regulated by signalling through the CTD code. Materne P, et al. Elife, 2015 Jun 22. PMID 26098123, Free PMC Article
    5. Large scale screening of genetic interaction with sgf73(+) in fission yeast. Guo Y, et al. Yi Chuan, 2014 Jul. PMID 25076038

    See all (16) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables chromatin binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables histone binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables histone chaperone activity IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in CENP-A eviction from euchromatin EXP
    Inferred from Experiment
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in CENP-A containing chromatin EXP
    Inferred from Experiment
    more info
    		 PubMed 
    is_active_in chromatin EXP
    Inferred from Experiment
    more info
    		 PubMed 
    located_in chromatin IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in chromatin IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in chromosome, centromeric region IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in nucleoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    CENP-A histone disassembly chaperone Ccp1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003423.3 Reference assembly

      Range
      2393472..2395581 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001356261.2 → NP_001342975.1  CENP-A histone disassembly chaperone Ccp1 [Schizosaccharomyces pombe]

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      Q9HGN2
      Conserved Domains (1) summary
      cl08298
      Location:11 → 198
      NAP; Nucleosome assembly protein (NAP)
    Nucleotide Protein
    Heading Accession and Version

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