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    cdc123 translation initiation factor eIF2 assembly protein [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2541870, updated on 18-Sep-2024

    Summary

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    Official Symbol
    cdc123
    Official Full Name
    translation initiation factor eIF2 assembly protein
    Primary source
    PomBase:SPAP27G11.03
    Locus tag
    SPOM_SPAP27G11.03
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See cdc123 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    2
    Sequence:
    Chromosome: I; NC_003424.3 (1613116..1614313)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene sterol transfer protein Osh3 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene TPR repeat-containing protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene tRNA-specific adenosine deaminase subunit Tad3 Neighboring gene HOPS complex subunit Vps41

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Thermofluor-Based Analysis of Protein Integrity and Ligand Interactions. Pinz S, et al. Methods Mol Biol, 2022. PMID 35796993, Free PMC Article
    2. Binding of human Cdc123 to eIF2γ. Cardenal Peralta C, et al. J Struct Biol, 2023 Sep. PMID 37507029
    3. Cdc123, a Cell Cycle Regulator Needed for eIF2 Assembly, Is an ATP-Grasp Protein with Unique Features. Panvert M, et al. Structure, 2015 Sep 1. PMID 26211610
    4. ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe. Matsuyama A, et al. Nat Biotechnol, 2006 Jul. PMID 16823372
    5. Transcription and RNA-processing in fission yeast mitochondria. Schäfer B, et al. RNA, 2005 May. PMID 15811919, Free PMC Article

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables ATP binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables magnesium ion binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables protein folding chaperone TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in eukaryotic translation initiation factor 2 complex assembly ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in cytosol HDA PubMed 

    General protein information

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    Preferred Names
    translation initiation factor eIF2 assembly protein

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      1613116..1614313
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001018840.3 → NP_593407.1  translation initiation factor eIF2 assembly protein [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_593407.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      Q9P7N5
      Conserved Domains (1) summary
      pfam07065
      Location:18 → 298
      D123; D123
    Nucleotide Protein
    Heading Accession and Version

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