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    hpt1 xanthine phosphoribosyltransferase [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2541970, updated on 18-Sep-2024

    Summary

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    Official Symbol
    hpt1
    Official Full Name
    xanthine phosphoribosyltransferase
    Primary source
    PomBase:SPAC23C11.13c
    Locus tag
    SPOM_SPAC23C11.13C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    Also known as
    pur1
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    Genomic context

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    See hpt1 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    2
    Sequence:
    Chromosome: I; NC_003424.3 (2155374..2156517, complement)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene serine/threonine protein kinase Cka1 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene anaphase-promoting complex TPR lobe accessory factor subunit Hcn1/Apc12 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The substrate specificity of purine phosphoribosyltransferases in Schizosaccharomyces pombe. De Groodt A, et al. Biochem J, 1971 May. PMID 5123876, Free PMC Article
    2. Purification and comparative study of adenine and guanine phosphoribosyltransferases from Schizosaccharomyces pombe. Nagy M, et al. Eur J Biochem, 1977 Jul 1. PMID 20306
    3. Study of the role of puring phosphoribosyltransferases in the uptake of adenine and guanine by Schizosaccharomyces pombe cells. Housset P, et al. Eur J Biochem, 1977 Feb 15. PMID 14008
    4. A central role for TOR signalling in a yeast model for juvenile CLN3 disease. Bond ME, et al. Microb Cell, 2015 Nov 11. PMID 28357272, Free PMC Article
    5. A Proteome-wide Fission Yeast Interactome Reveals Network Evolution Principles from Yeasts to Human. Vo TV, et al. Cell, 2016 Jan 14. PMID 26771498, Free PMC Article

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables guanine phosphoribosyltransferase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables hypoxanthine phosphoribosyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables hypoxanthine phosphoribosyltransferase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables pentosyltransferase activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    enables xanthine phosphoribosyltransferase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in GMP salvage EXP
    Inferred from Experiment
    more info
    		 PubMed 
    involved_in GMP salvage IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in GMP salvage IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in IMP salvage EXP
    Inferred from Experiment
    more info
    		 PubMed 
    involved_in IMP salvage IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in XMP salvage IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in hypoxanthine metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in purine ribonucleoside salvage IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in nucleus ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    xanthine phosphoribosyltransferase

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      2155374..2156517 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001019075.3 → NP_593644.1  xanthine phosphoribosyltransferase [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_593644.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O13917
      Conserved Domains (1) summary
      COG2236
      Location:2 → 197
      Hpt1; Hypoxanthine phosphoribosyltransferase [Coenzyme transport and metabolism]
    Nucleotide Protein
    Heading Accession and Version

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