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    urh1 uridine ribohydrolase [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2540168, updated on 18-Sep-2024

    Summary

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    Official Symbol
    urh1
    Official Full Name
    uridine ribohydrolase
    Primary source
    PomBase:SPBC1683.06c
    Locus tag
    SPOM_SPBC1683.06C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See urh1 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    1
    Sequence:
    Chromosome: II; NC_003423.3 (151789..152911, complement)

    Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene transporter Thi7 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene maltase alpha-glucosidase Mal1 Neighboring gene ncRNA Neighboring gene hexose transporter Ght4

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003423.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A genetic screen to discover pathways affecting cohesin function in Schizosaccharomyces pombe identifies chromatin effectors. Chen Z, et al. G3 (Bethesda), 2012 Oct. PMID 23050226, Free PMC Article
    2. A Proteome-wide Fission Yeast Interactome Reveals Network Evolution Principles from Yeasts to Human. Vo TV, et al. Cell, 2016 Jan 14. PMID 26771498, Free PMC Article
    3. Hierarchical modularity and the evolution of genetic interactomes across species. Ryan CJ, et al. Mol Cell, 2012 Jun 8. PMID 22681890, Free PMC Article
    4. ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe. Matsuyama A, et al. Nat Biotechnol, 2006 Jul. PMID 16823372
    5. Transcription and RNA-processing in fission yeast mitochondria. Schäfer B, et al. RNA, 2005 May. PMID 15811919, Free PMC Article

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables nicotinamide riboside hydrolase activity ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables nicotinic acid riboside hydrolase activity ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables purine nucleosidase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables uridine nucleosidase activity ISO
    Inferred from Sequence Orthology
    more info
    		  
    Process Evidence Code Pubs
    involved_in NAD biosynthesis via nicotinamide riboside salvage pathway ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in nicotinate nucleotide salvage ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in purine nucleoside catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in pyrimidine nucleoside catabolic process ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in pyrimidine-containing compound salvage ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytosol HDA PubMed 
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in nucleus HDA PubMed 

    General protein information

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    Preferred Names
    uridine ribohydrolase

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003423.3 Reference assembly

      Range
      151789..152911 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001020968.3 → NP_595062.1  uridine ribohydrolase [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_595062.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      Q9P6J4
      Conserved Domains (1) summary
      cd02651
      Location:2 → 306
      nuc_hydro_IU_UC_XIUA; nuc_hydro_IU_UC_XIUA: inosine-uridine preferring, xanthosine-inosine-uridine-adenosine-preferring and, uridine-cytidine preferring nucleoside hydrolases. Nucleoside hydrolases cleave the N-glycosidic bond in nucleosides generating ribose and the ...
    Nucleotide Protein
    Heading Accession and Version

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    Molecular Biology Databases
    Research Materials