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    skb5 Shk1 kinase-binding protein 5 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2539237, updated on 18-Sep-2024

    Summary

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    Official Symbol
    skb5
    Official Full Name
    Shk1 kinase-binding protein 5
    Primary source
    PomBase:SPCC24B10.13
    Locus tag
    SPOM_SPCC24B10.13
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    Also known as
    skb2
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    Genomic context

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    See skb5 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    1
    Sequence:
    Chromosome: III; NC_003421.2 (922634..923491)

    Chromosome III - NC_003421.2Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene THO complex subunit Tho7 Neighboring gene EKC/KEOPS complex subunit Cgi121 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene XRCC4-like factor xlf1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003421.2

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Direct activation of the fission yeast PAK Shk1 by the novel SH3 domain protein, Skb5. Yang P, et al. J Biol Chem, 1999 Dec 17. PMID 10593886
    2. Skb5, an SH3 adaptor protein, regulates Pmk1 MAPK signaling by controlling the intracellular localization of the MAPKKK Mkh1. Kanda Y, et al. J Cell Sci, 2016 Aug 15. PMID 27451356
    3. Yeast adaptor protein, Nbp2p, is conserved regulator of fungal Ptc1p phosphatases and is involved in multiple signaling pathways. Stanger K, et al. J Biol Chem, 2012 Jun 22. PMID 22570491, Free PMC Article
    4. Compartmentalized nodes control mitotic entry signaling in fission yeast. Deng L, et al. Mol Biol Cell, 2013 Jun. PMID 23615447, Free PMC Article
    5. Cross-species protein interactome mapping reveals species-specific wiring of stress response pathways. Das J, et al. Sci Signal, 2013 May 21. PMID 23695164, Free PMC Article

    See all (19) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein kinase activator activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in intracellular signal transduction IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in endoplasmic reticulum HDA PubMed 

    General protein information

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    Preferred Names
    Shk1 kinase-binding protein 5

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003421.2 Reference assembly

      Range
      922634..923491
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001023007.2 → NP_588016.1  Shk1 kinase-binding protein 5 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_588016.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      Q9US59
      Conserved Domains (1) summary
      cd11865
      Location:84 → 138
      SH3_Nbp2-like; Src Homology 3 domain of Saccharomyces cerevisiae Nap1-binding protein 2 and similar fungal proteins
    Nucleotide Protein
    Heading Accession and Version

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