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    qns1 glutamine-dependent NAD(+) synthetase [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2539475, updated on 18-Sep-2024

    Summary

    Official Symbol
    qns1
    Official Full Name
    glutamine-dependent NAD(+) synthetase
    Primary source
    PomBase:SPCC553.02
    Locus tag
    SPOM_SPCC553.02
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

    See qns1 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    6
    Sequence:
    Chromosome: III; NC_003421.2 (305618..308619, complement)

    Chromosome III - NC_003421.2Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene cyclophilin family peptidyl-prolyl cis-trans isomerase Cyp9 Neighboring gene AAA family ATPase Pex1 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene DNA recombination protein Dbl2

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables ATP binding ISM
    Inferred from Sequence Model
    more info
     
    enables NAD+ synthase (glutamine-hydrolyzing) activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables glutaminase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in NAD biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in cytosol HDA PubMed 
    is_active_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    glutamine-dependent NAD(+) synthetase

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003421.2 Reference assembly

      Range
      305618..308619 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001022764.3NP_587771.1  glutamine-dependent NAD(+) synthetase [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_587771.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O74940
      Conserved Domains (3) summary
      cd07570
      Location:6286
      GAT_Gln-NAD-synth; Glutamine aminotransferase (GAT, glutaminase) domain of glutamine-dependent NAD synthetases (class 7 and 8 nitrilases)
      PLN02339
      Location:3695
      PLN02339; NAD+ synthase (glutamine-hydrolysing)
      cd00553
      Location:330651
      NAD_synthase; NAD+ synthase is a homodimer, which catalyzes the final step in de novo nicotinamide adenine dinucleotide (NAD+) biosynthesis, an amide transfer from either ammonia or glutamine to nicotinic acid adenine dinucleotide (NaAD). The conversion of NaAD to NAD ...