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    cdc5 splicing factor Cdc5 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2543583, updated on 18-Sep-2024

    Summary

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    Official Symbol
    cdc5
    Official Full Name
    splicing factor Cdc5
    Primary source
    PomBase:SPAC644.12
    Locus tag
    SPOM_SPAC644.12
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    Also known as
    cef1
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    Genomic context

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    See cdc5 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    6
    Sequence:
    Chromosome: I; NC_003424.3 (2694699..2697430)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene [pyruvate dehydrogenase (acetyl-transferring)] kinase Pkp1 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Rab GTPase-binding protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene RecA family recombinase Rad51/Rhp51

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The Schizosaccharomyces pombe cdc5+ gene encodes an essential protein with homology to c-Myb. Ohi R, et al. EMBO J, 1994 Jan 15. PMID 8313892, Free PMC Article
    2. Structural and functional insights into the N-terminus of Schizosaccharomyces pombe Cdc5. Collier SE, et al. Biochemistry, 2014 Oct 21. PMID 25263959, Free PMC Article
    3. Structural and functional analysis of essential pre-mRNA splicing factor Prp19p. Ohi MD, et al. Mol Cell Biol, 2005 Jan. PMID 15601865, Free PMC Article
    4. Promoter-driven splicing regulation in fission yeast. Moldón A, et al. Nature, 2008 Oct 16. PMID 18815595
    5. The Prp19 WD40 domain contains a conserved protein interaction region essential for its function. Vander Kooi CW, et al. Structure, 2010 May 12. PMID 20462492, Free PMC Article

    See all (34) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables DNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in mRNA cis splicing, via spliceosome EXP
    Inferred from Experiment
    more info
    		 PubMed 
    involved_in mRNA cis splicing, via spliceosome IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in mRNA splicing, via spliceosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of Prp19 complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of Prp19 complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in cytosol IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in nucleolar peripheral inclusion body IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in nucleus HDA PubMed 
    is_active_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of post-mRNA release spliceosomal complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of spliceosomal complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of spliceosomal complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    splicing factor Cdc5

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      2694699..2697430
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001019310.3 → NP_593880.1  splicing factor Cdc5 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_593880.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      P39964
      Conserved Domains (4) summary
      cd11659
      Location:54 → 103
      SANT_CDC5_II; SANT/myb-like DNA-binding domain of Cell Division Cycle 5-Like Protein repeat II
      COG5147
      Location:1 → 535
      REB1; Myb superfamily proteins, including transcription factors and mRNA splicing factors [Transcription / RNA processing and modification / Cell division and chromosome partitioning]
      pfam11831
      Location:417 → 611
      Myb_Cef; pre-mRNA splicing factor component
      pfam13921
      Location:9 → 69
      Myb_DNA-bind_6; Myb-like DNA-binding domain
    Nucleotide Protein
    Heading Accession and Version

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