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    tfa2 transcription factor TFIIE subunit Tfa2 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2539236, updated on 18-Sep-2024

    Summary

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    Official Symbol
    tfa2
    Official Full Name
    transcription factor TFIIE subunit Tfa2
    Primary source
    PomBase:SPCC1672.08c
    Locus tag
    SPOM_SPCC1672.08C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See tfa2 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    1
    Sequence:
    Chromosome: III; NC_003421.2 (579220..580557, complement)

    Chromosome III - NC_003421.2Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene tRNA-Arg Neighboring gene ncRNA Neighboring gene triglyceride lipase-cholesterol esterase Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003421.2

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Studies of Schizosaccharomyces pombe TFIIE indicate conformational and functional changes in RNA polymerase II at transcription initiation. Hayashi K, et al. Genes Cells, 2005 Mar. PMID 15743411
    2. Mediator is required for activated transcription in a Schizosaccharomyces pombe in vitro system. Tamayo E, et al. Eur J Biochem, 2004 Jun. PMID 15182371
    3. RNA polymerase II initiation factor interactions and transcription start site selection. Li Y, et al. Science, 1994 Feb 11. PMID 8303296
    4. Conservation and rewiring of functional modules revealed by an epistasis map in fission yeast. Roguev A, et al. Science, 2008 Oct 17. PMID 18818364, Free PMC Article
    5. Chromatin remodeller Fun30(Fft3) induces nucleosome disassembly to facilitate RNA polymerase II elongation. Lee J, et al. Nat Commun, 2017 Feb 20. PMID 28218250, Free PMC Article

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables RNA polymerase II general transcription initiation factor activity EXP
    Inferred from Experiment
    more info
    		 PubMed 
    enables RNA polymerase II general transcription initiation factor activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    contributes_to TFIIH-class transcription factor complex binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in transcription initiation at RNA polymerase II promoter EXP
    Inferred from Experiment
    more info
    		 PubMed 
    involved_in transcription initiation at RNA polymerase II promoter IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in transcription initiation at RNA polymerase II promoter IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in nucleolus HDA PubMed 
    is_active_in nucleus HDA PubMed 
    part_of transcription factor TFIIE complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of transcription factor TFIIE complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    transcription factor TFIIE subunit Tfa2

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003421.2 Reference assembly

      Range
      579220..580557 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001022871.3 → NP_587879.1  transcription factor TFIIE subunit Tfa2 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_587879.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      P79011, Q5R228
      Conserved Domains (1) summary
      COG5174
      Location:1 → 284
      TFA2; Transcription initiation factor IIE, beta subunit [Transcription]
    Nucleotide Protein
    Heading Accession and Version

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