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    moe1 translation initiation factor eIF3d [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2543412, updated on 18-Sep-2024

    Summary

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    Official Symbol
    moe1
    Official Full Name
    translation initiation factor eIF3d
    Primary source
    PomBase:SPAC637.07
    Locus tag
    SPOM_SPAC637.07
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    Also known as
    tif304
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    Genomic context

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    See moe1 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    1
    Sequence:
    Chromosome: I; NC_003424.3 (4551840..4553741)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene V-type ATPase V1 subunit B Neighboring gene ncRNA Neighboring gene alpha-1,2-galactosyltransferase Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Fe-sulfur cluster assembly ATPase Nbp35 Neighboring gene putative ribonuclease H70

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A conserved interaction between Moe1 and Mal3 is important for proper spindle formation in Schizosaccharomyces pombe. Chen CR, et al. Mol Biol Cell, 2000 Dec. PMID 11102508, Free PMC Article
    2. Moe1 and spInt6, the fission yeast homologues of mammalian translation initiation factor 3 subunits p66 (eIF3d) and p48 (eIF3e), respectively, are required for stable association of eIF3 subunits. Bandyopadhyay A, et al. J Biol Chem, 2002 Jan 18. PMID 11705997
    3. Int6 and Moe1 interact with Cdc48 to regulate ERAD and proper chromosome segregation. Otero JH, et al. Cell Cycle, 2010 Jan 1. PMID 20016281, Free PMC Article
    4. A Transcript-Specific eIF3 Complex Mediates Global Translational Control of Energy Metabolism. Shah M, et al. Cell Rep, 2016 Aug 16. PMID 27477275, Free PMC Article
    5. Yin6, a fission yeast Int6 homolog, complexes with Moe1 and plays a role in chromosome segregation. Yen HC, et al. Proc Natl Acad Sci U S A, 2000 Dec 19. PMID 11121040, Free PMC Article

    See all (28) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. A transcript-specific eIF3 complex mediates global translational control of energy metabolism.
      Title: A Transcript-Specific eIF3 Complex Mediates Global Translational Control of Energy Metabolism.
    2. Results suggest that Cdc48, Yin6 and Moe1 act in the same protein complex to concertedly control ERAD and chromosome segregation.
      Title: Int6 and Moe1 interact with Cdc48 to regulate ERAD and proper chromosome segregation.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables translation initiation factor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in formation of cytoplasmic translation initiation complex IC
    Inferred by Curator
    more info
    		 PubMed 
    involved_in translational initiation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasmic stress granule EXP
    Inferred from Experiment
    more info
    		 PubMed 
    is_active_in cytosol HDA PubMed 
    is_active_in cytosol IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of eukaryotic 43S preinitiation complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of eukaryotic translation initiation factor 3 complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of eukaryotic translation initiation factor 3 complex, eIF3e IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of eukaryotic translation initiation factor 3 complex, eIF3m IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    translation initiation factor eIF3d

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      4551840..4553741
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001020053.3 → NP_594625.1  translation initiation factor eIF3d [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_594625.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O94236
      Conserved Domains (1) summary
      pfam05091
      Location:5 → 547
      eIF-3_zeta; Eukaryotic translation initiation factor 3 subunit 7 (eIF-3)
    Nucleotide Protein
    Heading Accession and Version

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