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    egt2 ergothioneine biosynthesis methyltransferase Egt2 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2541092, updated on 18-Sep-2024

    Summary

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    Official Symbol
    egt2
    Official Full Name
    ergothioneine biosynthesis methyltransferase Egt2
    Primary source
    PomBase:SPBC660.12c
    Locus tag
    SPOM_SPBC660.12C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See egt2 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    1
    Sequence:
    Chromosome: II; NC_003423.3 (215522..218349, complement)

    Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene protein mug168 Neighboring gene mitochondrial translation elongation factor G Neighboring gene single-stranded telomeric-binding protein Tgc1 Neighboring gene ncRNA Neighboring gene DNA replication factor A subunit Ssb1 Neighboring gene ncRNA Neighboring gene M phase inhibitor protein kinase Mik1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003423.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genetic and metabolomic dissection of the ergothioneine and selenoneine biosynthetic pathway in the fission yeast, S. pombe, and construction of an overproduction system. Pluskal T, et al. PLoS One, 2014. PMID 24828577, Free PMC Article
    2. Hierarchical modularity and the evolution of genetic interactomes across species. Ryan CJ, et al. Mol Cell, 2012 Jun 8. PMID 22681890, Free PMC Article
    3. ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe. Matsuyama A, et al. Nat Biotechnol, 2006 Jul. PMID 16823372
    4. Transcription and RNA-processing in fission yeast mitochondria. Schäfer B, et al. RNA, 2005 May. PMID 15811919, Free PMC Article
    5. The genome sequence of Schizosaccharomyces pombe. Wood V, et al. Nature, 2002 Feb 21. PMID 11859360

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables hercynylcysteine sulfoxide lyase activity (ergothioneine-forming) IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in ergothioneine biosynthetic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in selenoneine biosynthetic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in cytosol HDA PubMed 
    is_active_in nucleus HDA PubMed 

    General protein information

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    Preferred Names
    ergothioneine biosynthesis methyltransferase Egt2

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003423.3 Reference assembly

      Range
      215522..218349 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001020998.3 → NP_595091.1  ergothioneine biosynthesis methyltransferase Egt2 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_595091.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O94431
      Conserved Domains (2) summary
      COG0520
      Location:23 → 390
      CsdA; Selenocysteine lyase/Cysteine desulfurase [Amino acid transport and metabolism]
      cl18945
      Location:64 → 305
      AAT_I; Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the ...
    Nucleotide Protein
    Heading Accession and Version

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