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    cdc17 ATP-dependent DNA replication ligase Cdc17 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2541849, updated on 18-Sep-2024

    Summary

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    Official Symbol
    cdc17
    Official Full Name
    ATP-dependent DNA replication ligase Cdc17
    Primary source
    PomBase:SPAC20G8.01
    Locus tag
    SPOM_SPAC20G8.01
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See cdc17 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    3
    Sequence:
    Chromosome: I; NC_003424.3 (1387885..1390617)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene mitochondrial dihydroorotate dehydrogenase Ura3 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene DDHD family phospholipase Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genetic and enzymatic characterization of conditional lethal mutants of the yeast Schizosaccharomyces pombe with a temperature-sensitive DNA ligase. Nasmyth KA. J Mol Biol, 1979 May 25. PMID 469945
    2. Temperature-sensitive lethal mutants in the structural gene for DNA ligase in the yeast Schizosaccharomyces pombe. Nasmyth KA. Cell, 1977 Dec. PMID 597860
    3. The rad3+ gene of Schizosaccharomyces pombe is involved in multiple checkpoint functions and in DNA repair. Jimenez G, et al. Proc Natl Acad Sci U S A, 1992 Jun 1. PMID 1594599, Free PMC Article
    4. Cloning and characterization of the Schizosaccharomyces pombe DNA ligase gene CDC17. Johnston LH, et al. Gene, 1986. PMID 3011605
    5. Saccharomyces cerevisiae cdc9, a structural gene for yeast DNA ligase which complements Schizosaccharomyces pombe cdc17. Barker DG, et al. Eur J Biochem, 1983 Aug 1. PMID 6347688

    See all (34) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA ligase (ATP) activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables DNA ligase (ATP) activity IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    enables DNA ligase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables DNA ligase activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in DNA ligation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in DNA recombination ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in DNA repair IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in Okazaki fragment processing involved in mitotic DNA replication IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in Okazaki fragment processing involved in mitotic DNA replication IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in base-excision repair ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in lagging strand elongation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in mitochondrial DNA metabolic process IC
    Inferred by Curator
    more info
    		  
    involved_in nucleotide-excision repair ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in mitochondrion IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in nuclear replication fork IC
    Inferred by Curator
    more info
    		  
    is_active_in nucleus HDA PubMed 
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    ATP-dependent DNA replication ligase Cdc17

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      1387885..1390617
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001018749.3 → NP_593318.2  ATP-dependent DNA replication ligase Cdc17 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_593318.2

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      P12000
      Conserved Domains (4) summary
      cd07969
      Location:603 → 750
      OBF_DNA_ligase_I; The Oligonucleotide/oligosaccharide binding (OB)-fold domain of ATP-dependent DNA ligase I is a DNA-binding module that is part of the catalytic core unit
      cd07900
      Location:379 → 598
      Adenylation_DNA_ligase_I_Euk; Adenylation domain of eukaryotic DNA Ligase I
      PLN03113
      Location:20 → 751
      PLN03113; DNA ligase 1; Provisional
      pfam04675
      Location:149 → 319
      DNA_ligase_A_N; DNA ligase N terminus
    Nucleotide Protein
    Heading Accession and Version

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