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    ctr5 Cu transporter complex subunit Ctr5 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2542949, updated on 18-Sep-2024

    Summary

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    Official Symbol
    ctr5
    Official Full Name
    Cu transporter complex subunit Ctr5
    Primary source
    PomBase:SPAC1142.05
    Locus tag
    SPOM_SPAC1142.05
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See ctr5 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    1
    Sequence:
    Chromosome: I; NC_003424.3 (3635409..3636572)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene Noc complex Noc2 family subunit Neighboring gene 5S ribosomal RNA Neighboring gene ncRNA Neighboring gene GET complex ATPase subunit Get3 Neighboring gene ncRNA Neighboring gene ESCRT III complex subunit Vps32

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Copper-dependent trafficking of the Ctr4-Ctr5 copper transporting complex. Ioannoni R, et al. PLoS One, 2010 Aug 4. PMID 20694150, Free PMC Article
    2. Functional dissection of Ctr4 and Ctr5 amino-terminal regions reveals motifs with redundant roles in copper transport. Beaudoin J, et al. Microbiology (Reading), 2006 Jan. PMID 16385131
    3. Identification of a novel high affinity copper transport complex in the fission yeast Schizosaccharomyces pombe. Zhou H, et al. J Biol Chem, 2001 Jun 8. PMID 11274192
    4. Shu1 is a cell-surface protein involved in iron acquisition from heme in Schizosaccharomyces pombe. Mourer T, et al. J Biol Chem, 2015 Apr 17. PMID 25733668, Free PMC Article
    5. Dissection of the relative contribution of the Schizosaccharomyces pombe Ctr4 and Ctr5 proteins to the copper transport and cell surface delivery functions. Beaudoin J, et al. Microbiology (Reading), 2011 Apr. PMID 21273250, Free PMC Article

    See all (14) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. The authors propose that the Ctr4 central domain mediates Cu transport in this hetero-complex, whereas the Ctr5 carboxyl-terminal domains functions in the regulation of trafficking of the Cu transport complex to the cell surface. [Ctr4 & Ctr5]
      Title: Dissection of the relative contribution of the Schizosaccharomyces pombe Ctr4 and Ctr5 proteins to the copper transport and cell surface delivery functions.
    2. Ctr4 and Ctr5 proteins co-localize at the plasma membrane shortly after meiotic induction, whereas Ctr6 is located on the membrane of vacuoles.
      Title: Characterization of Schizosaccharomyces pombe copper transporter proteins in meiotic and sporulating cells.
    3. a copper-dependent internalization and recycling of the heteromeric Ctr4-Ctr5 complex
      Title: Copper-dependent trafficking of the Ctr4-Ctr5 copper transporting complex.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables copper ion transmembrane transporter activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in copper ion import across plasma membrane IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in copper ion transmembrane transport IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in fungal-type vacuole IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Cu transporter complex subunit Ctr5

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      3635409..3636572
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001019692.3 → NP_594269.1  Cu transporter complex subunit Ctr5 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_594269.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      Q9P7F9
      Conserved Domains (1) summary
      pfam04145
      Location:29 → 155
      Ctr; Ctr copper transporter family
    Nucleotide Protein
    Heading Accession and Version

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