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    LINC00663 long intergenic non-protein coding RNA 663 [ Homo sapiens (human) ]

    Gene ID: 284440, updated on 10-Dec-2024

    Summary

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    Official Symbol
    LINC00663provided by HGNC
    Official Full Name
    long intergenic non-protein coding RNA 663provided by HGNC
    Primary source
    HGNC:HGNC:28609
    See related
    MIM:617117; AllianceGenome:HGNC:28609
    Gene type
    ncRNA
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Expression
    Ubiquitous expression in thyroid (RPKM 1.9), ovary (RPKM 1.5) and 24 other tissues See more
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    Genomic context

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    See LINC00663 in Genome Data Viewer
    Location:
    19p13.11
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 19 NC_000019.10 (19756371..19776413, complement)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 19 NC_060943.1 (19894039..19914115, complement)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (19867180..19887222, complement)

    Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene zinc finger protein 14 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 10457 Neighboring gene uncharacterized LOC101060187 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr19:19858409-19858910 Neighboring gene sorting nexin 18 pseudogene Neighboring gene ATAC-STARR-seq lymphoblastoid active region 14370 Neighboring gene H3K27ac hESC enhancer GRCh37_chr19:19887366-19888257 Neighboring gene zinc finger protein 56, pseudogene Neighboring gene zinc finger protein 506 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 14372 Neighboring gene H3K27ac hESC enhancer GRCh37_chr19:19932265-19932779 Neighboring gene iron-sulfur cluster assembly 1 pseudogene 5

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Tissue-specific circular RNA induction during human fetal development
    • Description: 35 human fetal samples from 6 tissues (3 - 7 replicates per tissue) collected between 10 and 20 weeks gestational time were sequenced using Illumina TruSeq Stranded Total RNA
    • BioProject: PRJNA270632
    • Publication: PMID 26076956
    • Analysis date: Mon Apr 2 22:54:59 2018

    Bibliography

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    Related articles in PubMed

    1. The Effect and Mechanism of LINC00663 on the Biological Behavior of Glioma. Pan M, et al. Neurochem Res, 2021 Jul. PMID 33830405
    2. A novel variable exonic region and differential expression of LINC00663 non-coding RNA in various cancer cell lines and normal human tissue samples. Bozgeyik E, et al. Tumour Biol, 2016 Jul. PMID 26743782
    3. Differential expression of a set of genes in follicular and classic variants of papillary thyroid carcinoma. Igci YZ, et al. Endocr Pathol, 2011 Jun. PMID 21509594
    4. DCAF8, a novel MuRF1 interaction partner, promotes muscle atrophy. Nowak M, et al. J Cell Sci, 2019 Sep 6. PMID 31391242
    5. A germline-specific class of small RNAs binds mammalian Piwi proteins. Girard A, et al. Nature, 2006 Jul 13. PMID 16751776

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. The Effect and Mechanism of LINC00663 on the Biological Behavior of Glioma.
      Title: The Effect and Mechanism of LINC00663 on the Biological Behavior of Glioma.
    2. LINC00663 was shown to be differentially expressed in various human tissues and cancer cell lines.
      Title: A novel variable exonic region and differential expression of LINC00663 non-coding RNA in various cancer cell lines and normal human tissue samples.
    3. LOC284440 gene expression is decreased in follicular variant of papillary thyroid carcinoma.
      Title: Differential expression of a set of genes in follicular and classic variants of papillary thyroid carcinoma.
    Submit: New GeneRIF Correction

    Phenotypes

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    Review eQTL and phenotype association data in this region using PheGenI

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Potential readthrough

    Included gene: ZNF506

    Other Names

    • CTC-559E9.1

    Clone Names

    • FLJ12356, MGC39821

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    RNA

    1. NR_026956.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC011477, AK289657, BC034236, DB196080

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000019.10 Reference GRCh38.p14 Primary Assembly

      Range
      19756371..19776413 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060943.1 Alternate T2T-CHM13v2.0

      Range
      19894039..19914115 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_182576.1: Suppressed sequence

      Description
      NM_182576.1: This RefSeq record was removed by NCBI staff. Contact [email protected] for further information.
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.