ARHGEF10L Rho guanine nucleotide exchange factor 10 like [Homo sapiens (human)] - Gene

Summary

Official Symbol: ARHGEF10Lprovided by HGNC
Official Full Name: Rho guanine nucleotide exchange factor 10 likeprovided by HGNC
Primary source: HGNC:HGNC:25540
See related: Ensembl:ENSG00000074964 MIM:612494; AllianceGenome:HGNC:25540
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Homo sapiens
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as: GrinchGEF
Summary: This gene belongs to the RhoGEF subfamily of RhoGTPases. Members of this subfamily are activated by specific guanine nucleotide exchange factors (GEFs) and are involved in signal transduction. The encoded protein shows cytosolic distribution. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2016]
Expression: Ubiquitous expression in kidney (RPKM 7.7), colon (RPKM 6.9) and 24 other tissues See more
Orthologs: mouse all
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Genomic context

Location:: 1p36.13

Exon count:: 39

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCh38.p14 (GCF_000001405.40)	1	NC_000001.11 (17513435..17697875)
RS_2024_08	current	T2T-CHM13v2.0 (GCF_009914755.1)	1	NC_060925.1 (17327447..17513168)
RS_2024_09	previous assembly	GRCh37.p13 (GCF_000001405.25)	1	NC_000001.10 (17866193..18024370)

Chromosome 1 - NC_000001.11 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Tissue-specific circular RNA induction during human fetal development
Description: 35 human fetal samples from 6 tissues (3 - 7 replicates per tissue) collected between 10 and 20 weeks gestational time were sequenced using Illumina TruSeq Stranded Total RNA
BioProject: PRJNA270632
Publication: PMID 26076956
Analysis date: Mon Apr 2 22:54:59 2018

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

ARHGEF10L expression regulates cell proliferation and migration in gastric tumorigenesis.
Title: ARHGEF10L expression regulates cell proliferation and migration in gastric tumorigenesis.
increased expression of ARHGEF10L stimulates hepatocellular tumorigenesis by activating the RhoA-ROCK1- phospho Ezrin/Radixin/Moesin pathway and epithelial-mesenchymal transition.
Title: ARHGEF10L contributes to liver tumorigenesis through RhoA-ROCK1 signaling and the epithelial-mesenchymal transition.
Inherited variants in ARHGEF10L and AKAP6, with potential transcriptional regulatory function and association with Epithelial ovarian cancer risk, warrant investigation in independent Epithelial ovarian cancer study populations.
Title: Variants in genes encoding small GTPases and association with epithelial ovarian cancer susceptibility.
Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)
Title: Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.
Observational study of gene-disease association. (HuGE Navigator)
Title: Mutation of ARHGAP9 in patients with coronary spastic angina.
In intact cells, GrinchGEF induced specifically Rho activation and enhanced RhoA-C-specific downstream effects.
Title: GrinchGEF--a novel Rho-specific guanine nucleotide exchange factor.
Observational study and genome-wide association study of gene-disease association. (HuGE Navigator)
Title: Common variants on 1p36 and 1q42 are associated with cutaneous basal cell carcinoma but not with melanoma or pigmentation traits.

Submit: New GeneRIF Correction

Phenotypes

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Find tests for this gene in the NIH Genetic Testing Registry (GTR)

Review eQTL and phenotype association data in this region using PheGenI

EBI GWAS Catalog

Description
Common variants on 1p36 and 1q42 are associated with cutaneous basal cell carcinoma but not with melanoma or pigmentation traits. EBI GWAS Catalog EBI GWAS CatalogPubMed
Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population. EBI GWAS Catalog EBI GWAS CatalogPubMed
Serum ferritin levels are associated with a distinct phenotype of chronic hepatitis C poorly responding to pegylated interferon-alpha and ribavirin therapy. EBI GWAS Catalog EBI GWAS CatalogPubMed

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

D1S1954E (e-PCR)
- UniSTS:151303

D10S275 (e-PCR)
- UniSTS:147992

D8S2279 (e-PCR)
- UniSTS:473907

SHGC-74357 (e-PCR)
- UniSTS:36158

D1S544 (e-PCR)
- UniSTS:75849

SHGC-74299 (e-PCR)
- UniSTS:2891

HSC1HH062 (e-PCR)
- UniSTS:66430

L17877 (e-PCR)
- UniSTS:61334

D1S1474 (e-PCR)
- UniSTS:149670

G17701 (e-PCR)
- UniSTS:29099

SHGC-145764 (e-PCR)
- UniSTS:174776

D1S1283 (e-PCR)
- UniSTS:149480

Gene Ontology Provided by GOA

Function	Evidence Code	Pubs
enables GTPase activator activity	IDA Inferred from Direct Assay more info	PubMed
enables guanyl-nucleotide exchange factor activity	IBA Inferred from Biological aspect of Ancestor more info
enables guanyl-nucleotide exchange factor activity	TAS Traceable Author Statement more info

Process	Evidence Code	Pubs
involved_in SREBP signaling pathway	IBA Inferred from Biological aspect of Ancestor more info
involved_in SREBP signaling pathway	IDA Inferred from Direct Assay more info	PubMed
involved_in actin cytoskeleton organization	IBA Inferred from Biological aspect of Ancestor more info
involved_in positive regulation of stress fiber assembly	IBA Inferred from Biological aspect of Ancestor more info
involved_in positive regulation of stress fiber assembly	IDA Inferred from Direct Assay more info	PubMed
involved_in regulation of small GTPase mediated signal transduction	TAS Traceable Author Statement more info

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
is_active_in cytosol	IBA Inferred from Biological aspect of Ancestor more info
located_in cytosol	IDA Inferred from Direct Assay more info	PubMed
located_in cytosol	TAS Traceable Author Statement more info

General protein information

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Preferred Names: rho guanine nucleotide exchange factor 10-like protein

Names: Rho guanine nucleotide exchange factor (GEF) 10-like

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

NG_050860.2 RefSeqGene

Range

31265..189436

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_001011722.2 → NP_001011722.2 rho guanine nucleotide exchange factor 10-like protein isoform 2

See identical proteins and their annotated locations for NP_001011722.2

Status: REVIEWED

Description

Transcript Variant: This variant (2) lacks an in-frame exon, as compared to variant 1. The encoded isoform 2 thus lacks an internal segment, as compared to isoform 1.

Source sequence(s)

AB046846, AK092020, AW455769, BC080596

Consensus CDS

CCDS30617.1

UniProtKB/TrEMBL

A0A2X0U2F8

Related

ENSP00000364564.1, ENST00000375415.5

Conserved Domains (3) summary

pfam00621
Location:285 → 463

RhoGEF; RhoGEF domain

sd00039
Location:888 → 931

7WD40; WD40 repeat [structural motif]

cl02567
Location:861 → 1011

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
NM_001319837.1 → NP_001306766.1 rho guanine nucleotide exchange factor 10-like protein isoform 3

Status: REVIEWED

Description

Transcript Variant: This variant (3) lacks two alternate in-frame exons in the 5' coding region, compared to variant 1. It encodes isoform 3, which lacks two separate internal in-frame segments and is shorter than isoform 1.

Source sequence(s)

AB046846, BC111058, BU738615, DQ139833

UniProtKB/TrEMBL

A0A2X0U2F8

Conserved Domains (3) summary

pfam00621
Location:285 → 463

RhoGEF; RhoGEF domain

sd00039
Location:883 → 926

7WD40; WD40 repeat [structural motif]

cl02567
Location:856 → 1006

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
NM_001319838.1 → NP_001306767.1 rho guanine nucleotide exchange factor 10-like protein isoform 4

Status: REVIEWED

Description

Transcript Variant: This variant (4) represents use of an alternate promoter. It differs in the 5' UTR and 5' coding region, uses an alternate start codon and lacks three alternate exons in the coding region, compared to variant 1. It encodes isoform 4, which is shorter and has a distinct N-terminus, compared to isoform 1.

Source sequence(s)

AK092020, BC111058, BU738615, DA468685, DQ139833

UniProtKB/TrEMBL

B3KX74

Conserved Domains (3) summary

sd00039
Location:630 → 673

7WD40; WD40 repeat [structural motif]

cl02567
Location:603 → 753

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

cl02571
Location:102 → 210

RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
NM_001328124.1 → NP_001315053.1 rho guanine nucleotide exchange factor 10-like protein isoform 5

Status: REVIEWED

Description

Transcript Variant: This variant (5) represents use of an alternate promoter and contains novel 5' UTR and 5' coding region, compared to variant 1. It encodes isoform 5, which is shorter and has a distinct N-terminus, compared to isoform 1.

Source sequence(s)

AK092020, AK300264, BC080596, BC111058, DA468685

UniProtKB/TrEMBL

B3KX74

Conserved Domains (3) summary

pfam00621
Location:102 → 280

RhoGEF; RhoGEF domain

sd00039
Location:705 → 748

7WD40; WD40 repeat [structural motif]

cl02567
Location:678 → 828

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
NM_018125.4 → NP_060595.3 rho guanine nucleotide exchange factor 10-like protein isoform 1

See identical proteins and their annotated locations for NP_060595.3

Status: REVIEWED

Description

Transcript Variant: This variant (1) encodes the longer isoform (1).

Source sequence(s)

AB046846, AK092020, AL390994, AW455769, BC065561

Consensus CDS

CCDS182.1

UniProtKB/Swiss-Prot

B7ZKS1, Q17RW1, Q3YFJ4, Q5VXI5, Q5VXI6, Q66K51, Q6P0L7, Q8NAV5, Q9HCE6, Q9NVT3

UniProtKB/TrEMBL

A0A2X0U2F8

Related

ENSP00000355060.3, ENST00000361221.8

Conserved Domains (2) summary

cd00160
Location:317 → 501

RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.

sd00039
Location:927 → 970

7WD40; WD40 repeat [structural motif]

RNA

NR_137287.2 RNA Sequence

Status: REVIEWED

Description

Transcript Variant: This variant (6) contains an alternate internal exon, compared to variant 1. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).

Source sequence(s)

AB046846, AK092020, AL358593, AL390994, BC111058
NR_137288.2 RNA Sequence

Status: REVIEWED

Description

Transcript Variant: This variant (7) lacks an alternate internal exon and contains an additional internal exon, compared to variant 1. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).

Source sequence(s)

AB046846, AK092020, AL358593, AL390994, BC111058

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

NC_000001.11 Reference GRCh38.p14 Primary Assembly

Range

17513435..17697875

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_024448061.2 → XP_024303829.1 rho guanine nucleotide exchange factor 10-like protein isoform X1

UniProtKB/TrEMBL

A0A2X0U2F8

Conserved Domains (2) summary

cd00160
Location:282 → 466

RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.

sd00039
Location:892 → 935

7WD40; WD40 repeat [structural motif]
XM_006710728.1 → XP_006710791.1 rho guanine nucleotide exchange factor 10-like protein isoform X1

See identical proteins and their annotated locations for XP_006710791.1

UniProtKB/TrEMBL

A0A2X0U2F8

Conserved Domains (2) summary

cd00160
Location:282 → 466

RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.

sd00039
Location:892 → 935

7WD40; WD40 repeat [structural motif]
XM_047424089.1 → XP_047280045.1 rho guanine nucleotide exchange factor 10-like protein isoform X6

UniProtKB/TrEMBL

A0A2X0U2F8
XM_006710731.1 → XP_006710794.1 rho guanine nucleotide exchange factor 10-like protein isoform X2

See identical proteins and their annotated locations for XP_006710794.1

UniProtKB/TrEMBL

A0A2X0U2F8

Conserved Domains (3) summary

pfam00621
Location:288 → 466

RhoGEF; RhoGEF domain

sd00039
Location:891 → 934

7WD40; WD40 repeat [structural motif]

cl02567
Location:864 → 1014

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
XM_047424111.1 → XP_047280067.1 rho guanine nucleotide exchange factor 10-like protein isoform X7

UniProtKB/TrEMBL

A0A2X0U2F8
XM_047424100.1 → XP_047280056.1 rho guanine nucleotide exchange factor 10-like protein isoform X7

UniProtKB/TrEMBL

A0A2X0U2F8
XM_047424075.1 → XP_047280031.1 rho guanine nucleotide exchange factor 10-like protein isoform X1

UniProtKB/TrEMBL

A0A2X0U2F8
XM_005245923.3 → XP_005245980.2 rho guanine nucleotide exchange factor 10-like protein isoform X1

See identical proteins and their annotated locations for XP_005245980.2

UniProtKB/TrEMBL

A0A2X0U2F8

Conserved Domains (2) summary

cd00160
Location:282 → 466

RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.

sd00039
Location:892 → 935

7WD40; WD40 repeat [structural motif]
XM_047424093.1 → XP_047280049.1 rho guanine nucleotide exchange factor 10-like protein isoform X6

UniProtKB/TrEMBL

A0A2X0U2F8
XM_006710729.2 → XP_006710792.1 rho guanine nucleotide exchange factor 10-like protein isoform X2

See identical proteins and their annotated locations for XP_006710792.1

UniProtKB/TrEMBL

A0A2X0U2F8

Conserved Domains (3) summary

pfam00621
Location:288 → 466

RhoGEF; RhoGEF domain

sd00039
Location:891 → 934

7WD40; WD40 repeat [structural motif]

cl02567
Location:864 → 1014

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
XM_005245925.3 → XP_005245982.2 rho guanine nucleotide exchange factor 10-like protein isoform X4

See identical proteins and their annotated locations for XP_005245982.2

UniProtKB/TrEMBL

A0A2X0U2F8

Conserved Domains (3) summary

pfam00621
Location:285 → 463

RhoGEF; RhoGEF domain

sd00039
Location:888 → 931

7WD40; WD40 repeat [structural motif]

cl02567
Location:861 → 1011

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
XM_017001617.2 → XP_016857106.1 rho guanine nucleotide exchange factor 10-like protein isoform X7

UniProtKB/TrEMBL

A0A2X0U2F8

Conserved Domains (3) summary

pfam00621
Location:285 → 463

RhoGEF; RhoGEF domain

sd00039
Location:883 → 926

7WD40; WD40 repeat [structural motif]

cl02567
Location:856 → 1006

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
XM_047424065.1 → XP_047280021.1 rho guanine nucleotide exchange factor 10-like protein isoform X1

UniProtKB/TrEMBL

A0A2X0U2F8
XM_047424097.1 → XP_047280053.1 rho guanine nucleotide exchange factor 10-like protein isoform X6

UniProtKB/TrEMBL

A0A2X0U2F8
XM_047424112.1 → XP_047280068.1 rho guanine nucleotide exchange factor 10-like protein isoform X7

UniProtKB/TrEMBL

A0A2X0U2F8
XM_047424071.1 → XP_047280027.1 rho guanine nucleotide exchange factor 10-like protein isoform X1

UniProtKB/TrEMBL

A0A2X0U2F8
XM_047424070.1 → XP_047280026.1 rho guanine nucleotide exchange factor 10-like protein isoform X1

UniProtKB/TrEMBL

A0A2X0U2F8
XM_024448059.2 → XP_024303827.1 rho guanine nucleotide exchange factor 10-like protein isoform X1

UniProtKB/TrEMBL

A0A2X0U2F8

Conserved Domains (2) summary

cd00160
Location:282 → 466

RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.

sd00039
Location:892 → 935

7WD40; WD40 repeat [structural motif]
XM_047424098.1 → XP_047280054.1 rho guanine nucleotide exchange factor 10-like protein isoform X7

UniProtKB/TrEMBL

A0A2X0U2F8
XM_024448062.1 → XP_024303830.1 rho guanine nucleotide exchange factor 10-like protein isoform X1

UniProtKB/TrEMBL

A0A2X0U2F8

Conserved Domains (2) summary

cd00160
Location:282 → 466

RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.

sd00039
Location:892 → 935

7WD40; WD40 repeat [structural motif]
XM_047424096.1 → XP_047280052.1 rho guanine nucleotide exchange factor 10-like protein isoform X6

UniProtKB/TrEMBL

A0A2X0U2F8
XM_047424105.1 → XP_047280061.1 rho guanine nucleotide exchange factor 10-like protein isoform X7

UniProtKB/TrEMBL

A0A2X0U2F8
XM_011541692.3 → XP_011539994.1 rho guanine nucleotide exchange factor 10-like protein isoform X5

UniProtKB/TrEMBL

A0A2X0U2F8

Conserved Domains (3) summary

pfam00621
Location:289 → 467

RhoGEF; RhoGEF domain

sd00039
Location:887 → 930

7WD40; WD40 repeat [structural motif]

cl02567
Location:860 → 1010

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
XM_011541691.3 → XP_011539993.1 rho guanine nucleotide exchange factor 10-like protein isoform X3

UniProtKB/TrEMBL

A0A2X0U2F8

Conserved Domains (3) summary

pfam00621
Location:286 → 464

RhoGEF; RhoGEF domain

sd00039
Location:889 → 932

7WD40; WD40 repeat [structural motif]

cl02567
Location:862 → 1012

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
XM_017001619.2 → XP_016857108.1 rho guanine nucleotide exchange factor 10-like protein isoform X9
XM_017001620.2 → XP_016857109.1 rho guanine nucleotide exchange factor 10-like protein isoform X10
XM_047424158.1 → XP_047280114.1 rho guanine nucleotide exchange factor 10-like protein isoform X11
XM_047424175.1 → XP_047280131.1 rho guanine nucleotide exchange factor 10-like protein isoform X15
XM_047424159.1 → XP_047280115.1 rho guanine nucleotide exchange factor 10-like protein isoform X12
XM_047424190.1 → XP_047280146.1 rho guanine nucleotide exchange factor 10-like protein isoform X16
XM_047424165.1 → XP_047280121.1 rho guanine nucleotide exchange factor 10-like protein isoform X13
XM_047424167.1 → XP_047280123.1 rho guanine nucleotide exchange factor 10-like protein isoform X14
XM_047424201.1 → XP_047280157.1 rho guanine nucleotide exchange factor 10-like protein isoform X17
XM_005245929.4 → XP_005245986.2 rho guanine nucleotide exchange factor 10-like protein isoform X8

UniProtKB/TrEMBL

B3KX74, Q5VXI4

Related

ENSP00000364557.3, ENST00000375408.7

Conserved Domains (3) summary

pfam00621
Location:102 → 280

RhoGEF; RhoGEF domain

sd00039
Location:700 → 743

7WD40; WD40 repeat [structural motif]

cl02567
Location:673 → 823

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

RNA

XR_946686.4 RNA Sequence
XR_946691.3 RNA Sequence

Alternate T2T-CHM13v2.0

Genomic

NC_060925.1 Alternate T2T-CHM13v2.0

Range

17327447..17513168

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_054337380.1 → XP_054193355.1 rho guanine nucleotide exchange factor 10-like protein isoform X1

UniProtKB/TrEMBL

A0A2X0U2F8
XM_054337377.1 → XP_054193352.1 rho guanine nucleotide exchange factor 10-like protein isoform X1

UniProtKB/TrEMBL

A0A2X0U2F8
XM_054337389.1 → XP_054193364.1 rho guanine nucleotide exchange factor 10-like protein isoform X6

UniProtKB/TrEMBL

A0A2X0U2F8
XM_054337384.1 → XP_054193359.1 rho guanine nucleotide exchange factor 10-like protein isoform X2

UniProtKB/TrEMBL

A0A2X0U2F8
XM_054337396.1 → XP_054193371.1 rho guanine nucleotide exchange factor 10-like protein isoform X7

UniProtKB/TrEMBL

A0A2X0U2F8
XM_054337394.1 → XP_054193369.1 rho guanine nucleotide exchange factor 10-like protein isoform X7

UniProtKB/TrEMBL

A0A2X0U2F8
XM_054337383.1 → XP_054193358.1 rho guanine nucleotide exchange factor 10-like protein isoform X1

UniProtKB/TrEMBL

A0A2X0U2F8
XM_054337376.1 → XP_054193351.1 rho guanine nucleotide exchange factor 10-like protein isoform X1

UniProtKB/TrEMBL

A0A2X0U2F8
XM_054337390.1 → XP_054193365.1 rho guanine nucleotide exchange factor 10-like protein isoform X6

UniProtKB/TrEMBL

A0A2X0U2F8
XM_054337385.1 → XP_054193360.1 rho guanine nucleotide exchange factor 10-like protein isoform X2

UniProtKB/TrEMBL

A0A2X0U2F8
XM_054337387.1 → XP_054193362.1 rho guanine nucleotide exchange factor 10-like protein isoform X4

UniProtKB/TrEMBL

A0A2X0U2F8
XM_054337398.1 → XP_054193373.1 rho guanine nucleotide exchange factor 10-like protein isoform X7

UniProtKB/TrEMBL

A0A2X0U2F8
XM_054337375.1 → XP_054193350.1 rho guanine nucleotide exchange factor 10-like protein isoform X1

UniProtKB/TrEMBL

A0A2X0U2F8
XM_054337392.1 → XP_054193367.1 rho guanine nucleotide exchange factor 10-like protein isoform X6

UniProtKB/TrEMBL

A0A2X0U2F8
XM_054337397.1 → XP_054193372.1 rho guanine nucleotide exchange factor 10-like protein isoform X7

UniProtKB/TrEMBL

A0A2X0U2F8
XM_054337382.1 → XP_054193357.1 rho guanine nucleotide exchange factor 10-like protein isoform X1

UniProtKB/TrEMBL

A0A2X0U2F8
XM_054337393.1 → XP_054193368.1 rho guanine nucleotide exchange factor 10-like protein isoform X7

UniProtKB/TrEMBL

A0A2X0U2F8
XM_054337381.1 → XP_054193356.1 rho guanine nucleotide exchange factor 10-like protein isoform X1

UniProtKB/TrEMBL

A0A2X0U2F8
XM_054337378.1 → XP_054193353.1 rho guanine nucleotide exchange factor 10-like protein isoform X1

UniProtKB/TrEMBL

A0A2X0U2F8
XM_054337379.1 → XP_054193354.1 rho guanine nucleotide exchange factor 10-like protein isoform X1

UniProtKB/TrEMBL

A0A2X0U2F8
XM_054337391.1 → XP_054193366.1 rho guanine nucleotide exchange factor 10-like protein isoform X6

UniProtKB/TrEMBL

A0A2X0U2F8
XM_054337395.1 → XP_054193370.1 rho guanine nucleotide exchange factor 10-like protein isoform X7

UniProtKB/TrEMBL

A0A2X0U2F8
XM_054337388.1 → XP_054193363.1 rho guanine nucleotide exchange factor 10-like protein isoform X5

UniProtKB/TrEMBL

A0A2X0U2F8
XM_054337386.1 → XP_054193361.1 rho guanine nucleotide exchange factor 10-like protein isoform X3

UniProtKB/TrEMBL

A0A2X0U2F8
XM_054337400.1 → XP_054193375.1 rho guanine nucleotide exchange factor 10-like protein isoform X9
XM_054337401.1 → XP_054193376.1 rho guanine nucleotide exchange factor 10-like protein isoform X10
XM_054337402.1 → XP_054193377.1 rho guanine nucleotide exchange factor 10-like protein isoform X11
XM_054337406.1 → XP_054193381.1 rho guanine nucleotide exchange factor 10-like protein isoform X15
XM_054337403.1 → XP_054193378.1 rho guanine nucleotide exchange factor 10-like protein isoform X12
XM_054337407.1 → XP_054193382.1 rho guanine nucleotide exchange factor 10-like protein isoform X16
XM_054337404.1 → XP_054193379.1 rho guanine nucleotide exchange factor 10-like protein isoform X13
XM_054337405.1 → XP_054193380.1 rho guanine nucleotide exchange factor 10-like protein isoform X14
XM_054337408.1 → XP_054193383.1 rho guanine nucleotide exchange factor 10-like protein isoform X17
XM_054337399.1 → XP_054193374.1 rho guanine nucleotide exchange factor 10-like protein isoform X8

UniProtKB/TrEMBL

B3KX74