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    Mir503hg Mir503, Mir351, and Mir322 host gene [ Mus musculus (house mouse) ]

    Gene ID: 72575, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Mir503hgprovided by MGI
    Official Full Name
    Mir503, Mir351, and Mir322 host geneprovided by MGI
    Primary source
    MGI:MGI:5579436
    See related
    AllianceGenome:MGI:5579436
    Gene type
    ncRNA
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Gm28730; LncSync; mir-322; mir-351; mir-503; Hrtlincrx; 2700063P19Rik; 9430052C07Rik; C430049B03Rik
    Summary
    Is expressed in several structures, including extraembryonic component; forelimb bud; gut; heart and pericardium; and pectoral girdle and thoracic body wall muscle. [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in placenta adult (RPKM 20.1), limb E14.5 (RPKM 16.4) and 5 other tissues See more
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    Genomic context

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    See Mir503hg in Genome Data Viewer
    Location:
    X A5; X 29.31 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) X NC_000086.8 (52141989..52146067, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) X NC_000086.7 (53053112..53057190, complement)

    Chromosome X - NC_000086.8Genomic Context describing neighboring genes Neighboring gene Uncharacterized LOC119919412 Neighboring gene microRNA 450-2 Neighboring gene predicted gene, 57846 Neighboring gene STARR-seq mESC enhancer starr_47192 Neighboring gene microRNA 542 Neighboring gene microRNA 351 Neighboring gene microRNA 503 Neighboring gene microRNA 322 Neighboring gene predicted gene, 35988 Neighboring gene placental specific protein 1 Neighboring gene PABIR family member 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. A long non-coding RNA LncSync regulates mouse cardiomyocyte homeostasis and cardiac hypertrophy through coordination of miRNA actions. Huang R, et al. Protein Cell, 2023 Mar 16. PMID 36929003, Free PMC Article
    2. Minimal in vivo requirements for developmentally regulated cardiac long intergenic non-coding RNAs. George MR, et al. Development, 2019 Dec 9. PMID 31784461, Free PMC Article
    3. USP7 represses lineage differentiation genes in mouse embryonic stem cells by both catalytic and noncatalytic activities. Liu C, et al. Sci Adv, 2023 May 19. PMID 37196079, Free PMC Article
    4. miRBase: integrating microRNA annotation and deep-sequencing data. Kozomara A, et al. Nucleic Acids Res, 2011 Jan. PMID 21037258, Free PMC Article
    5. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. A long non-coding RNA LncSync regulates mouse cardiomyocyte homeostasis and cardiac hypertrophy through coordination of miRNA actions.
      Title: A long non-coding RNA LncSync regulates mouse cardiomyocyte homeostasis and cardiac hypertrophy through coordination of miRNA actions.
    Submit: New GeneRIF Correction

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Other Names

    • Mir503 Mir531 and Mir322 host

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    RNA

    1. NR_038184.1 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript.
      Source sequence(s)
      BX649621

    2. NR_038185.1 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) uses an alternate splice site in an internal exon, compared to variant 1.
      Source sequence(s)
      AK021262, BX649621

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000086.8 Reference GRCm39 C57BL/6J

      Range
      52141989..52146067 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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