art-1 putative very-long-chain enoyl-CoA reductase art-1 [Caenorhabditis elegans] - Gene

Summary

Go to the top of the page Help

Official Symbol: art-1
Official Full Name: putative very-long-chain enoyl-CoA reductase art-1
Primary source: WormBase:WBGene00000198
Locus tag: CELE_C15F1.6
See related: AllianceGenome:WB:WBGene00000198
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable oxidoreductase activity. Predicted to be involved in very long-chain fatty acid biosynthetic process. Predicted to be located in endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in autosomal recessive intellectual developmental disorder 14 and catecholaminergic polymorphic ventricular tachycardia 3. Orthologous to several human genes including TECR (trans-2,3-enoyl-CoA reductase). [provided by Alliance of Genome Resources, Dec 2024]
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help

See art-1 in Genome Data Viewer

Location:: chromosome: II

Exon count:: 5

Sequence:: Chromosome: II; NC_003280.10 (6970745..6972235, complement)

Chromosome II - NC_003280.10 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:: NC_003280.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

Pathways from PubChem

Go to the top of the page

Interactions

Go to the top of the page Help

Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

Go to the top of the page Help

Markers

C15F1.b (e-PCR)
- UniSTS:322493

C15F1.c (e-PCR)
- UniSTS:322494

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
enables oxidoreductase activity	IBA Inferred from Biological aspect of Ancestor more info
enables oxidoreductase activity	IEA Inferred from Electronic Annotation more info
enables oxidoreductase activity, acting on the CH-CH group of donors	IEA Inferred from Electronic Annotation more info
enables very-long-chain enoyl-CoA reductase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in fatty acid biosynthetic process	IEA Inferred from Electronic Annotation more info
involved_in lipid metabolic process	IEA Inferred from Electronic Annotation more info
involved_in very long-chain fatty acid biosynthetic process	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
located_in endoplasmic reticulum	IEA Inferred from Electronic Annotation more info
located_in endoplasmic reticulum membrane	IEA Inferred from Electronic Annotation more info
located_in membrane	IEA Inferred from Electronic Annotation more info

General protein information

Go to the top of the page Help

Preferred Names: putative very-long-chain enoyl-CoA reductase art-1

NP_495430.1

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003280.10 Reference assembly

Range

6970745..6972235 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_063029.7 → NP_495430.1 putative very-long-chain enoyl-CoA reductase art-1 [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_495430.1

Status: REVIEWED

UniProtKB/Swiss-Prot

Q9N5Y2

Conserved Domains (3) summary

cd01801
Location:5 → 82

Tsc13_N; Ubiquitin-like domain of Tsc13

PLN02560
Location:23 → 307

PLN02560; enoyl-CoA reductase

cl21511
Location:155 → 308

PEMT; Phospholipid methyltransferase