U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    lin-66 GATA-type domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 178354, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    lin-66
    Official Full Name
    GATA-type domain-containing protein
    Primary source
    WormBase:WBGene00001562
    Locus tag
    CELE_B0513.1
    See related
    AllianceGenome:WB:WBGene00001562
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Involved in negative regulation of gene expression and regulation of development, heterochronic. Located in cytoplasm. Is expressed in body wall musculature; hypodermis; intestine; neurons; and vulval muscle. [provided by Alliance of Genome Resources, Dec 2024]
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See lin-66 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    7
    Sequence:
    Chromosome: IV; NC_003282.8 (13888079..13893986)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003282.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. C. elegans LIN-66 mediates EIF-3/eIF3-dependent protein translation via a cold-shock domain. Blazie SM, et al. Life Sci Alliance, 2024 Sep. PMID 38886018, Free PMC Article
    2. Multiple mechanisms are involved in regulating the expression of the developmental timing regulator lin-28 in Caenorhabditis elegans. Morita K, et al. EMBO J, 2006 Dec 13. PMID 17139256, Free PMC Article
    3. The zinc-finger protein SEA-2 regulates larval developmental timing and adult lifespan in C. elegans. Huang X, et al. Development, 2011 May. PMID 21471153
    4. miRNAs give worms the time of their lives: small RNAs and temporal control in Caenorhabditis elegans. Resnick TD, et al. Dev Dyn, 2010 May. PMID 20232378, Free PMC Article
    5. Isolation of the interacting molecules with GEX-3 by a novel functional screening. Tsuboi D, et al. Biochem Biophys Res Commun, 2002 Apr 5. PMID 11922622

    See all (14) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. C. elegans LIN-66 mediates EIF-3/eIF3-dependent protein translation via a cold-shock domain.
      Title: C. elegans LIN-66 mediates EIF-3/eIF3-dependent protein translation via a cold-shock domain.
    Submit: New GeneRIF Correction

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in negative regulation of gene expression IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in negative regulation of gene expression IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of development, heterochronic IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in regulation of development, heterochronic IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    GATA-type domain-containing protein
    NP_001255767.1
    • Confirmed by transcript evidence
    NP_001255768.1
    • Confirmed by transcript evidence
    NP_001293994.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      13888079..13893986
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001307065.3 → NP_001293994.1  GATA-type domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001293994.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A061AL58

    2. NM_001268838.4 → NP_001255767.1  GATA-type domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001255767.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      O62020

    3. NM_001268839.3 → NP_001255768.1  GATA-type domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001255768.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      D3YT69
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools