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    hrg-9 Transport and Golgi organization protein 2 homolog [ Caenorhabditis elegans ]

    Gene ID: 179780, updated on 9-Dec-2024

    Summary

    Official Symbol
    hrg-9
    Official Full Name
    Transport and Golgi organization protein 2 homolog
    Primary source
    WormBase:WBGene00011305
    Locus tag
    CELE_R186.1
    See related
    AllianceGenome:WB:WBGene00011305
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be involved in Golgi organization and protein secretion. Predicted to be active in Golgi apparatus. Is expressed in intestine. Used to study chromosome 22q11.2 deletion syndrome, distal. Human ortholog(s) of this gene implicated in TANGO2-related metabolic encephalopathy and arrythmias. Orthologous to human TANGO2 (transport and golgi organization 2 homolog). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See hrg-9 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    5
    Sequence:
    Chromosome: V; NC_003283.11 (12961474..12963343, complement)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene D-aminoacyl-tRNA deacylase Neighboring gene Eukaryotic translation initiation factor 3 subunit K Neighboring gene Rhodanese domain-containing protein Neighboring gene ncRNA Neighboring gene G_PROTEIN_RECEP_F1_2 domain-containing protein;Serpentine Receptor, class D (delta) Neighboring gene Signal recognition particle receptor subunit beta

    General gene information

    Markers

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in Golgi organization IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in protein secretion IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in Golgi apparatus IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    Transport and Golgi organization protein 2 homolog
    NP_506243.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      12961474..12963343 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_073842.4NP_506243.1  Transport and Golgi organization protein 2 homolog [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_506243.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q22009
      Conserved Domains (1) summary
      pfam05742
      Location:1259
      TANGO2; Transport and Golgi organization 2