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    Y43B11AR.3 TruB_N domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 177480, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Y43B11AR.3
    Official Full Name
    TruB_N domain-containing protein
    Primary source
    WormBase:WBGene00021544
    Locus tag
    CELE_Y43B11AR.3
    See related
    AllianceGenome:WB:WBGene00021544
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable RNA binding activity and pseudouridine synthase activity. Predicted to be involved in pseudouridine synthesis. Orthologous to human TRUB2 (TruB pseudouridine synthase family member 2). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See Y43B11AR.3 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    6
    Sequence:
    Chromosome: IV; NC_003282.8 (7082217..7083716, complement)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene MS Related Protein Neighboring gene ncRNA Neighboring gene Small ribosomal subunit protein eS4 Neighboring gene Vinculin Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003282.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Functional identification of microRNA-centered complexes in C. elegans. Hebbar S, et al. Sci Rep, 2022 May 3. PMID 35504914, Free PMC Article
    2. A map of the interactome network of the metazoan C. elegans. Li S, et al. Science, 2004 Jan 23. PMID 14704431, Free PMC Article
    3. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables pseudouridine synthase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in RNA modification IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in pseudouridine synthesis IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    TruB_N domain-containing protein
    NP_501102.4
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      7082217..7083716 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_068701.8 → NP_501102.4  TruB_N domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_501102.4

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9N3X3
      Conserved Domains (1) summary
      cl00130
      Location:12 → 277
      PseudoU_synth; Pseudouridine synthases catalyze the isomerization of specific uridines in an RNA molecule to pseudouridines (5-ribosyluracil, psi)
    Nucleotide Protein
    Heading Accession and Version

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