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    ilc-17.1 Interleukin cytokine-related protein 17.1 [ Caenorhabditis elegans ]

    Gene ID: 188767, updated on 9-Dec-2024

    Summary

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    Official Symbol
    ilc-17.1
    Official Full Name
    Interleukin cytokine-related protein 17.1
    Primary source
    WormBase:WBGene00011937
    Locus tag
    CELE_T22H6.1
    See related
    AllianceGenome:WB:WBGene00011937
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable cytokine activity. Involved in positive regulation of locomotion and response to oxygen levels. Located in extracellular region. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See ilc-17.1 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    6
    Sequence:
    Chromosome: X; NC_003284.9 (12766818..12769797, complement)

    Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene Nuclear hormone receptor family member nhr-27 Neighboring gene ncRNA Neighboring gene Choline/ethanolaminephosphotransferase 1-like Neighboring gene Glutamate 5-kinase Neighboring gene Seven TM Receptor

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003284.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Neuronal IL-17 controls Caenorhabditis elegans developmental diapause through CEP-1/p53. Godthi A, et al. Proc Natl Acad Sci U S A, 2024 Mar 19. PMID 38483995, Free PMC Article
    2. IL-17: good fear no tears. Rua R, et al. Nat Immunol, 2020 Nov. PMID 32958929
    3. IL-17 is a neuromodulator of Caenorhabditis elegans sensory responses. Chen C, et al. Nature, 2017 Feb 2. PMID 28099418, Free PMC Article
    4. MALT-1 mediates IL-17 neural signaling to regulate C. elegans behavior, immunity and longevity. Flynn SM, et al. Nat Commun, 2020 Apr 29. PMID 32350248, Free PMC Article
    5. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables cytokine activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in positive regulation of locomotion IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in response to oxygen levels IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in extracellular region IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Interleukin cytokine-related protein 17.1
    NP_510131.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003284.9 Reference assembly

      Range
      12766818..12769797 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_077730.4 → NP_510131.2  Interleukin cytokine-related protein 17.1 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_510131.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q22687
      Conserved Domains (1) summary
      pfam06083
      Location:123 → 198
      IL17; Interleukin-17
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q22687.2

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