mma-1 Leucine-rich PPR motif-containing protein, mitochondrial [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: mma-1
Official Full Name: Leucine-rich PPR motif-containing protein, mitochondrial
Primary source: WormBase:WBGene00007587
Locus tag: CELE_C14C10.4
See related: AllianceGenome:WB:WBGene00007587
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable mRNA 3'-UTR binding activity. Predicted to be involved in regulation of mitochondrial translation. Predicted to be active in mitochondrion and nucleus. [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See mma-1 in Genome Data Viewer

Location:: chromosome: V

Exon count:: 7

Sequence:: Chromosome: V; NC_003283.11 (12592568..12596296, complement)

Chromosome V - NC_003283.11 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003283.11

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Data indicate that C14C10.4/MMA-1 Is the Structural and functional homolog of mammalian LRPPRC.
Title: Impaired complex IV activity in response to loss of LRPPRC function can be compensated by mitochondrial hyperfusion.

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

C14C10.4 (e-PCR)
- UniSTS:306010

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
enables mRNA 3'-UTR binding	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in regulation of mitochondrial translation	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in mitochondrion	IBA Inferred from Biological aspect of Ancestor more info
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: Leucine-rich PPR motif-containing protein, mitochondrial

NP_506151.1

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

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Reference assembly

Genomic

NC_003283.11 Reference assembly

Range

12592568..12596296 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_073750.6 → NP_506151.1 Leucine-rich PPR motif-containing protein, mitochondrial [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_506151.1

Status: REVIEWED

UniProtKB/TrEMBL

Q17974

Conserved Domains (1) summary

PRK04778
Location:693 → 954

PRK04778; septation ring formation regulator EzrA; Provisional