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    mms-19 MMS19 nucleotide excision repair protein [ Caenorhabditis elegans ]

    Gene ID: 178935, updated on 9-Dec-2024

    Summary

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    Official Symbol
    mms-19
    Official Full Name
    MMS19 nucleotide excision repair protein
    Primary source
    WormBase:WBGene00016060
    Locus tag
    CELE_C24G6.3
    See related
    AllianceGenome:WB:WBGene00016060
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be involved in protein maturation by iron-sulfur cluster transfer. Predicted to be located in cytoplasm; nucleus; and spindle. Predicted to be part of cytosolic [4Fe-4S] assembly targeting complex. Orthologous to human MMS19 (MMS19 homolog, cytosolic iron-sulfur assembly component). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See mms-19 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    17
    Sequence:
    Chromosome: V; NC_003283.11 (5514348..5520458)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene Nuclear hormone receptor family member nhr-47 Neighboring gene Amine oxidase domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene receptor protein-tyrosine kinase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003283.11

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Discovery of novel alternatively spliced C. elegans transcripts by computational analysis of SAGE data. Ruzanov P, et al. BMC Genomics, 2007 Nov 30. PMID 18053145, Free PMC Article
    2. ABCE1 is a highly conserved RNA silencing suppressor. Kärblane K, et al. PLoS One, 2015. PMID 25659154, Free PMC Article
    3. C. elegans ORFeome version 1.1: experimental verification of the genome annotation and resource for proteome-scale protein expression. Reboul J, et al. Nat Genet, 2003 May. PMID 12679813
    4. A map of the interactome network of the metazoan C. elegans. Li S, et al. Science, 2004 Jan 23. PMID 14704431, Free PMC Article
    5. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in DNA repair IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in iron-sulfur cluster assembly IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in protein maturation by iron-sulfur cluster transfer IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in protein maturation by iron-sulfur cluster transfer IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of cytosolic [4Fe-4S] assembly targeting complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of cytosolic [4Fe-4S] assembly targeting complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in spindle IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    MMS19 nucleotide excision repair protein
    NP_504457.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      5514348..5520458
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_072056.5 → NP_504457.2  MMS19 nucleotide excision repair protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_504457.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      O76384
      Conserved Domains (1) summary
      pfam14500
      Location:60 → 296
      MMS19_N; Dos2-interacting transcription regulator of RNA-Pol-II
    Nucleotide Protein
    Heading Accession and Version

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