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    F58A6.1 Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial [ Caenorhabditis elegans ]

    Gene ID: 186486, updated on 9-Dec-2024

    Summary

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    Official Symbol
    F58A6.1
    Official Full Name
    Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial
    Primary source
    WormBase:WBGene00019022
    Locus tag
    CELE_F58A6.1
    See related
    AllianceGenome:WB:WBGene00019022
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable delta(3,5)-delta(2,4)-dienoyl-CoA isomerase activity. Predicted to be involved in fatty acid beta-oxidation. Predicted to be active in mitochondrion. Orthologous to human ECH1 (enoyl-CoA hydratase 1). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See F58A6.1 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    5
    Sequence:
    Chromosome: II; NC_003280.10 (5142919..5144021)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene Transmembrane protein Neighboring gene Zinc metalloproteinase nas-29 Neighboring gene ncRNA Neighboring gene Uncharacterized protein Neighboring gene Serpentine receptor class beta-16

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003280.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables delta(3,5)-delta(2,4)-dienoyl-CoA isomerase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables isomerase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in fatty acid beta-oxidation IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in fatty acid metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial
    NP_494954.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      5142919..5144021
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_062553.7 → NP_494954.1  Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_494954.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q20959
      Conserved Domains (1) summary
      cl23717
      Location:1 → 275
      crotonase-like; Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. ...
    Nucleotide Protein
    Heading Accession and Version

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