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    mog-3 Pre-mRNA-splicing factor CWC25 homolog [ Caenorhabditis elegans ]

    Gene ID: 175730, updated on 9-Dec-2024

    Summary

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    Official Symbol
    mog-3
    Official Full Name
    Pre-mRNA-splicing factor CWC25 homolog
    Primary source
    WormBase:WBGene00003391
    Locus tag
    CELE_F52C9.7
    See related
    AllianceGenome:WB:WBGene00003391
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Involved in feminization of hermaphroditic germ-line and meiotic cell cycle. Located in nucleus. Is expressed in germ line. Orthologous to human CWC25 (CWC25 spliceosome associated protein homolog). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See mog-3 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    7
    Sequence:
    Chromosome: III; NC_003281.10 (5308602..5311136)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene non-specific serine/threonine protein kinase Neighboring gene Uncharacterized protein Neighboring gene tRNA-Thr Neighboring gene ncRNA Neighboring gene Putative RNA exonuclease pqe-1 Neighboring gene Uncharacterized protein Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003281.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The C. elegans sex determination protein MOG-3 functions in meiosis and binds to the CSL co-repressor CIR-1. Kasturi P, et al. Dev Biol, 2010 Aug 15. PMID 20478293
    2. Mate searching in Caenorhabditis elegans: a genetic model for sex drive in a simple invertebrate. Lipton J, et al. J Neurosci, 2004 Aug 25. PMID 15329389, Free PMC Article
    3. Gametogenesis: keeping the male element under control. Kuwabara PE. Curr Biol, 1998 Apr 9. PMID 9550693
    4. More mog genes that influence the switch from spermatogenesis to oogenesis in the hermaphrodite germ line of Caenorhabditis elegans. Graham PL, et al. Dev Genet, 1993. PMID 8111975
    5. mag-1, a homolog of Drosophila mago nashi, regulates hermaphrodite germ-line sex determination in Caenorhabditis elegans. Li W, et al. Dev Biol, 2000 Feb 15. PMID 10656761

    See all (16) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in RNA splicing IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in feminization of hermaphroditic germ-line IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in mRNA processing IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in mRNA splicing, via spliceosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in meiotic cell cycle IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of U2-type spliceosomal complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of spliceosomal complex IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Pre-mRNA-splicing factor CWC25 homolog
    NP_498134.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      5308602..5311136
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_065733.7 → NP_498134.1  Pre-mRNA-splicing factor CWC25 homolog [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_498134.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      G5EBT5
      Conserved Domains (1) summary
      pfam12542
      Location:7 → 99
      CWC25; Pre-mRNA splicing factor
    Nucleotide Protein
    Heading Accession and Version

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