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    cey-2 CSD domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 172219, updated on 9-Dec-2024

    Summary

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    Official Symbol
    cey-2
    Official Full Name
    CSD domain-containing protein
    Primary source
    WormBase:WBGene00000473
    Locus tag
    CELE_F46F11.2
    See related
    AllianceGenome:WB:WBGene00000473
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable nucleic acid binding activity. Predicted to be involved in regulation of gene expression. Part of ribonucleoprotein complex. Is expressed in germ cell; germ line; pharynx; and somatic cell. Used to study Huntington's disease and neurodegenerative disease. Orthologous to human YBX2 (Y-box binding protein 2). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See cey-2 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    3
    Sequence:
    Chromosome: I; NC_003279.8 (5619569..5620669)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene Trafficking protein particle complex subunit 8 Neighboring gene ncRNA Neighboring gene F-box domain-containing protein Neighboring gene Tenascin Neighboring gene RNA (guanine-9-)-methyltransferase domain-containing protein 1 Neighboring gene C2H2-type domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003279.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. cdk-7 Is required for mRNA transcription and cell cycle progression in Caenorhabditis elegans embryos. Wallenfang MR, et al. Proc Natl Acad Sci U S A, 2002 Apr 16. PMID 11960010, Free PMC Article
    2. A complex containing the Sm protein CAR-1 and the RNA helicase CGH-1 is required for embryonic cytokinesis in Caenorhabditis elegans. Audhya A, et al. J Cell Biol, 2005 Oct 24. PMID 16247027, Free PMC Article
    3. GLD-1, a cytoplasmic protein essential for oocyte differentiation, shows stage- and sex-specific expression during Caenorhabditis elegans germline development. Jones AR, et al. Dev Biol, 1996 Nov 25. PMID 8948583
    4. Genome-wide analysis of GLD-1-mediated mRNA regulation suggests a role in mRNA storage. Scheckel C, et al. PLoS Genet, 2012 May. PMID 22693456, Free PMC Article
    5. RNA as a target of double-stranded RNA-mediated genetic interference in Caenorhabditis elegans. Montgomery MK, et al. Proc Natl Acad Sci U S A, 1998 Dec 22. PMID 9860998, Free PMC Article

    See all (31) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables nucleic acid binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of gene expression IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of ribonucleoprotein complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    CSD domain-containing protein
    NP_491645.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      5619569..5620669
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_059244.7 → NP_491645.1  CSD domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_491645.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      P91306
      Conserved Domains (1) summary
      pfam00313
      Location:66 → 136
      CSD; 'Cold-shock' DNA-binding domain
    Nucleotide Protein
    Heading Accession and Version

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