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    dod-24 CUB-like domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 178245, updated on 9-Dec-2024

    Summary

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    Official Symbol
    dod-24
    Official Full Name
    CUB-like domain-containing protein
    Primary source
    WormBase:WBGene00007875
    Locus tag
    CELE_C32H11.12
    See related
    AllianceGenome:WB:WBGene00007875
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Involved in defense response to Gram-negative bacterium. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See dod-24 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    3
    Sequence:
    Chromosome: IV; NC_003282.8 (12940106..12941354, complement)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene CUB-like domain-containing protein Neighboring gene SXP/RAL-2 family protein Ani s 5-like cation-binding domain-containing protein Neighboring gene CUB-like domain-containing protein Neighboring gene ncRNA Neighboring gene G-protein coupled receptors family 1 profile domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003282.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A conserved PMK-1/p38 MAPK is required in caenorhabditis elegans tissue-specific immune response to Yersinia pestis infection. Bolz DD, et al. J Biol Chem, 2010 Apr 2. PMID 20133945, Free PMC Article
    2. Hsp90-downregulation influences the heat-shock response, innate immune response and onset of oocyte development in nematodes. Eckl J, et al. PLoS One, 2017. PMID 29078207, Free PMC Article
    3. Two neurons mediate diet-restriction-induced longevity in C. elegans. Bishop NA, et al. Nature, 2007 May 31. PMID 17538612
    4. Loss of Sirt1 function improves intestinal anti-bacterial defense and protects from colitis-induced colorectal cancer. Lo Sasso G, et al. PLoS One, 2014. PMID 25013930, Free PMC Article
    5. Regulation of fatty acid desaturase- and immunity gene-expression by mbk-1/DYRK1A in Caenorhabditis elegans. Mack HID, et al. BMC Genomics, 2022 Jan 4. PMID 34983389, Free PMC Article

    See all (17) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in defense response to Gram-negative bacterium IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in innate immune response HEP PubMed 

    General protein information

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    Preferred Names
    CUB-like domain-containing protein
    NP_502474.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      12940106..12941354 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_070073.8 → NP_502474.1  CUB-like domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_502474.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9XUH3
      Conserved Domains (1) summary
      pfam02408
      Location:16 → 137
      CUB_2; CUB-like domain
    Nucleotide Protein
    Heading Accession and Version

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