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    icap-1 Integrin Cytoplasmic domain-Associated Protein homolog [ Caenorhabditis elegans ]

    Gene ID: 189926, updated on 9-Dec-2024

    Summary

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    Official Symbol
    icap-1
    Official Full Name
    Integrin Cytoplasmic domain-Associated Protein homolog
    Primary source
    WormBase:WBGene00012889
    Locus tag
    CELE_Y45F10D.10
    See related
    AllianceGenome:WB:WBGene00012889
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be involved in integrin-mediated signaling pathway. Orthologous to human ITGB1BP1 (integrin subunit beta 1 binding protein 1). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See icap-1 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    5
    Sequence:
    Chromosome: IV; NC_003282.8 (13785743..13786961, complement)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene Putative polypeptide N-acetylgalactosaminyltransferase 10;Ricin B lectin domain-containing protein Neighboring gene Beta-lactamase-related domain-containing protein Neighboring gene NIF system FeS cluster assembly NifU N-terminal domain-containing protein Neighboring gene Spindle assembly abnormal protein 6 Neighboring gene WD_REPEATS_REGION domain-containing protein Neighboring gene Abnormal cell migration protein 18-like fibronectin type I domain-containing protein Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003282.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A conserved CCM complex promotes apoptosis non-autonomously by regulating zinc homeostasis. Chapman EM, et al. Nat Commun, 2019 Apr 17. PMID 30996251, Free PMC Article
    2. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
    3. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
    4. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in integrin-mediated signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Integrin Cytoplasmic domain-Associated Protein homolog
    NP_001255757.1
    • Confirmed by transcript evidence;
      Product from WormBase gene class icap
    NP_001255758.1
    • Confirmed by transcript evidence;
      Product from WormBase gene class icap

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      13785743..13786961 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001268828.2 → NP_001255757.1  Integrin Cytoplasmic domain-Associated Protein homolog [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001255757.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      O62480
      Conserved Domains (1) summary
      cl17171
      Location:25 → 136
      PH-like; Pleckstrin homology-like domain

    2. NM_001268829.4 → NP_001255758.1  Integrin Cytoplasmic domain-Associated Protein homolog [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001255758.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      D3NQ97
      Conserved Domains (1) summary
      cl17171
      Location:1 → 77
      PH-like; Pleckstrin homology-like domain
    Nucleotide Protein
    Heading Accession and Version

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