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    luc-7L LUC7 related splicing factor homolog [ Caenorhabditis elegans ]

    Gene ID: 174246, updated on 9-Dec-2024

    Summary

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    Official Symbol
    luc-7L
    Official Full Name
    LUC7 related splicing factor homolog
    Primary source
    WormBase:WBGene00015207
    Locus tag
    CELE_B0495.8
    See related
    AllianceGenome:WB:WBGene00015207
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable mRNA binding activity. Predicted to be involved in mRNA splice site recognition. Predicted to be part of U1 snRNP and U2-type prespliceosome. Orthologous to several human genes including LUC7L (LUC7 like). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See luc-7L in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    8
    Sequence:
    Chromosome: II; NC_003280.10 (7705533..7707483, complement)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene Protein moa-2 Neighboring gene Cyclin-dependent kinase 11.1 Neighboring gene Putative endoplasmic reticulum metallopeptidase 1-A Neighboring gene Uncharacterized protein Neighboring gene Serpentine receptor class epsilon-1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003280.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Evaluation of changes in Caenorhabditis elegans immune response during bacterial infection: a single nematode approach. Prithika U, et al. Microbes Infect, 2021 Nov-Dec. PMID 34091025
    2. The C. elegans glycopeptide hormone receptor ortholog, FSHR-1, regulates germline differentiation and survival. Cho S, et al. Curr Biol, 2007 Feb 6. PMID 17276913
    3. SIN-3 acts in distinct complexes to regulate the germline transcriptional program in Caenorhabditis elegans. Robert VJ, et al. Development, 2023 Nov 1. PMID 37818613, Free PMC Article
    4. Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules. Cipriani PG, et al. Elife, 2021 Jul 5. PMID 34223818, Free PMC Article
    5. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables mRNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables mRNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in mRNA splice site recognition IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in mRNA splice site recognition IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of U1 snRNP IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of U1 snRNP IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of U2-type prespliceosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    LUC7 related splicing factor homolog
    NP_741025.1
    • Confirmed by transcript evidence;
      Product from WormBase gene class luc
    NP_741026.1
    • Confirmed by transcript evidence;
      Product from WormBase gene class luc

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      7705533..7707483 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_171023.4 → NP_741026.1  LUC7 related splicing factor homolog [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_741026.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      G8JXY3
      Conserved Domains (1) summary
      COG5200
      Location:1 → 56
      LUC7; U1 snRNP component, mediates U1 snRNP association with cap-binding complex [RNA processing and modification]

    2. NM_171022.6 → NP_741025.1  LUC7 related splicing factor homolog [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_741025.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q09217
      Conserved Domains (2) summary
      COG5200
      Location:1 → 245
      LUC7; U1 snRNP component, mediates U1 snRNP association with cap-binding complex [RNA processing and modification]
      pfam03194
      Location:3 → 246
      LUC7; LUC7 N_terminus
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q09217.1

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