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    unc-132 NadR/Ttd14 AAA domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 178787, updated on 9-Dec-2024

    Summary

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    Official Symbol
    unc-132
    Official Full Name
    NadR/Ttd14 AAA domain-containing protein
    Primary source
    WormBase:WBGene00021078
    Locus tag
    CELE_W08A12.1
    See related
    AllianceGenome:WB:WBGene00021078
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable GTP binding activity; phosphatidic acid binding activity; and phosphatidylinositol binding activity. Predicted to be involved in photoreceptor cell maintenance. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See unc-132 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    9
    Sequence:
    Chromosome: V; NC_003283.11 (3687106..3701915)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene pseudo Neighboring gene Uncharacterized protein Neighboring gene Neuropeptide-Like Protein Neighboring gene DIOX_N domain-containing protein;ELM2 domain-containing protein Neighboring gene ncRNA Neighboring gene Transmembrane protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003283.11

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Transcriptional upregulation of both egl-1 BH3-only and ced-3 caspase is required for the death of the male-specific CEM neurons. Nehme R, et al. Cell Death Differ, 2010 Aug. PMID 20150917, Free PMC Article
    2. Depletion of endogenously biotinylated carboxylases enhances the sensitivity of TurboID-mediated proximity labeling in Caenorhabditis elegans. Artan M, et al. J Biol Chem, 2022 Sep. PMID 35933017, Free PMC Article
    3. Interactome analysis of Caenorhabditis elegans synapses by TurboID-based proximity labeling. Artan M, et al. J Biol Chem, 2021 Sep. PMID 34416233, Free PMC Article
    4. Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules. Cipriani PG, et al. Elife, 2021 Jul 5. PMID 34223818, Free PMC Article
    5. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables GTP binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables phosphatidic acid binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables phosphatidylinositol binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in photoreceptor cell maintenance IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    NadR/Ttd14 AAA domain-containing protein
    NP_001041178.1
    • Partially confirmed by transcript evidence
    NP_001317835.1
    • Confirmed by transcript evidence
    NP_504029.1
    • Confirmed by transcript evidence
    NP_504030.2
    • Partially confirmed by transcript evidence
    NP_741519.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      3687106..3701915
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_071628.5 → NP_504029.1  NadR/Ttd14 AAA domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_504029.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q95ZK4
      Conserved Domains (1) summary
      pfam13521
      Location:50 → 230
      AAA_28; AAA domain

    2. NM_171443.6 → NP_741519.1  NadR/Ttd14 AAA domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_741519.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      H2L0N0
      Conserved Domains (1) summary
      pfam13521
      Location:44 → 224
      AAA_28; AAA domain

    3. NM_071629.6 → NP_504030.2  NadR/Ttd14 AAA domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_504030.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      O01619
      Conserved Domains (1) summary
      pfam13521
      Location:107 → 287
      AAA_28; AAA domain

    4. NM_001330803.3 → NP_001317835.1  NadR/Ttd14 AAA domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A168H9Z7
      Conserved Domains (1) summary
      pfam13521
      Location:25 → 205
      AAA_28; AAA domain

    5. NM_001047713.3 → NP_001041178.1  NadR/Ttd14 AAA domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001041178.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      H2L0N1
      Conserved Domains (1) summary
      pfam13521
      Location:91 → 271
      AAA_28; AAA domain

    RNA

    1. NR_138515.1 RNA Sequence

      Status: REVIEWED

    2. NR_138516.1 RNA Sequence

      Status: REVIEWED

    Nucleotide Protein
    Heading Accession and Version

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