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    clec-47 C-type lectin domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 180025, updated on 9-Dec-2024

    Summary

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    Official Symbol
    clec-47
    Official Full Name
    C-type lectin domain-containing protein
    Primary source
    WormBase:WBGene00011668
    Locus tag
    CELE_T09F5.9
    See related
    AllianceGenome:WB:WBGene00011668
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable carbohydrate binding activity and pattern recognition receptor activity. Involved in response to gamma radiation. Predicted to be located in membrane. Predicted to be active in external side of plasma membrane. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See clec-47 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    2
    Sequence:
    Chromosome: V; NC_003283.11 (15175759..15176324)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene pseudo Neighboring gene pseudo Neighboring gene pseudo Neighboring gene DUF1248 domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003283.11

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Gene expression profiling studies on Caenorhabditis elegans dystrophin mutants dys-1(cx-35) and dys-1(cx18). Towers PR, et al. Genomics, 2006 Nov. PMID 16962739
    2. Identification and Functional Analysis of Cytokine-Like Protein CLEC-47 in Caenorhabditis elegans. Pan W, et al. mBio, 2021 Oct 26. PMID 34634942, Free PMC Article
    3. The DNA damage-inducible C. elegans tankyrase is a nuclear protein closely linked to chromosomes. White C, et al. Mol Cell Biochem, 2009 Apr. PMID 19104912
    4. Caenorhabditis elegans mounts a p38 MAPK pathway-mediated defence to Cutibacterium acnes infection. Huang X, et al. Cell Microbiol, 2020 Oct. PMID 32543022
    5. A tRNA processing enzyme is a key regulator of the mitochondrial unfolded protein response. Held JP, et al. Elife, 2022 Apr 22. PMID 35451962, Free PMC Article

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Identification and Functional Analysis of Cytokine-Like Protein CLEC-47 in Caenorhabditis elegans.
      Title: Identification and Functional Analysis of Cytokine-Like Protein CLEC-47 in Caenorhabditis elegans.
    Submit: New GeneRIF Correction

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables carbohydrate binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables pattern recognition receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in immune response IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in response to gamma radiation IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in external side of plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    C-type lectin domain-containing protein
    NP_506744.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      15175759..15176324
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_074343.7 → NP_506744.1  C-type lectin domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_506744.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      O18076
      Conserved Domains (1) summary
      smart00034
      Location:23 → 155
      CLECT; C-type lectin (CTL) or carbohydrate-recognition domain (CRD)
    Nucleotide Protein
    Heading Accession and Version

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