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    cyp-33C6 CYtochrome P450 family [ Caenorhabditis elegans ]

    Gene ID: 185591, updated on 9-Dec-2024

    Summary

    Official Symbol
    cyp-33C6
    Official Full Name
    CYtochrome P450 family
    Primary source
    WormBase:WBGene00018264
    Locus tag
    CELE_F41B5.7
    See related
    AllianceGenome:WB:WBGene00018264
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable heme binding activity; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; and steroid hydroxylase activity. Predicted to be involved in organic acid metabolic process and xenobiotic metabolic process. Predicted to be active in cytoplasm and intracellular membrane-bounded organelle. Human ortholog(s) of this gene implicated in end stage renal disease and renal hypertension. Orthologous to human CYP2C8 (cytochrome P450 family 2 subfamily C member 8). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See cyp-33C6 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    5
    Sequence:
    Chromosome: V; NC_003283.11 (2247254..2249410, complement)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene CYtochrome P450 family Neighboring gene CYtochrome P450 family Neighboring gene CYtochrome P450 family Neighboring gene Seven TM Receptor

    General gene information

    Markers

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in organic acid metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in xenobiotic metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in intracellular membrane-bounded organelle IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    CYtochrome P450 family
    NP_001303728.1
    • Confirmed by transcript evidence
    NP_001368585.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      2247254..2249410 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001316799.2NP_001303728.1  CYtochrome P450 family [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0M7RF98
      Conserved Domains (1) summary
      pfam00067
      Location:26478
      p450; Cytochrome P450
    2. NM_001380616.1NP_001368585.1  CYtochrome P450 family [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0M9JJ78
      Conserved Domains (1) summary
      cd20617
      Location:25440
      CYP1_2-like; cytochrome P450 families 1 and 2, and similar cytochrome P450s