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    clip-1 CAP-Gly domain-containing linker protein 1 homolog [ Caenorhabditis elegans ]

    Gene ID: 176307, updated on 9-Dec-2024

    Summary

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    Official Symbol
    clip-1
    Official Full Name
    CAP-Gly domain-containing linker protein 1 homolog
    Primary source
    WormBase:WBGene00010796
    Locus tag
    CELE_M01A8.2
    See related
    AllianceGenome:WB:WBGene00010796
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Enables microtubule binding activity. Involved in nucleus localization and nucleus organization. Located in nuclear envelope. Is expressed in pharynx. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See clip-1 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    20
    Sequence:
    Chromosome: III; NC_003281.10 (9260175..9269062, complement)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene putative RING finger protein T02C1.1 Neighboring gene RING-type E3 ubiquitin transferase Neighboring gene Uncharacterized protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Formin-homology and zinc finger domains protein 1 Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003281.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Dynactin binding to tyrosinated microtubules promotes centrosome centration in C. elegans by enhancing dynein-mediated organelle transport. Barbosa DJ, et al. PLoS Genet, 2017 Jul. PMID 28759579, Free PMC Article
    2. Amphiphysin 2 Orchestrates Nucleus Positioning and Shape by Linking the Nuclear Envelope to the Actin and Microtubule Cytoskeleton. D'Alessandro M, et al. Dev Cell, 2015 Oct 26. PMID 26506308
    3. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
    4. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables microtubule binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in nucleus localization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in nucleus organization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nuclear envelope IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    CAP-Gly domain-containing linker protein 1 homolog
    NP_001022682.1
    • Confirmed by transcript evidence
    NP_001022683.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      9260175..9269062 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001027511.6 → NP_001022682.1  CAP-Gly domain-containing linker protein 1 homolog [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001022682.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P34531, P34532, P34533, Q65ZC5
      Conserved Domains (1) summary
      pfam01302
      Location:22 → 85
      CAP_GLY; CAP-Gly domain

    2. NM_001027512.7 → NP_001022683.1  CAP-Gly domain-containing linker protein 1 homolog [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001022683.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P34531
      Conserved Domains (1) summary
      pfam01302
      Location:22 → 85
      CAP_GLY; CAP-Gly domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P34531.4

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